Pain Management

Knee Load Associated With Increased Walking Pain in Osteoarthritis

Knee Load Associated With Increased Walking Pain in Osteoarthritis

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Researchers examine the association between the knee adduction moment and increased knee pain during walking in patients with knee osteoarthritis.

Widespread Pain Common, Linked to Worse Patient-Reported Disease Activity in PsA

Widespread Pain Common, Linked to Worse Patient-Reported Disease Activity in PsA

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Widespread nonarthritic pain is linked to worse patient-reported and composite psoriatic arthritis activity measures.

Endocannabinoids May Be Elevated in Women With Fibromyalgia

Endocannabinoids May Be Elevated in Women With Fibromyalgia

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Women with fibromyalgia were found to have elevated levels of endocannabinoidome lipid mediators.

Higher PainDETECT Scores, Neuropathic Pain Preoperatively May Increase Risk for Chronic Pain Post-TKR

Higher PainDETECT Scores, Neuropathic Pain Preoperatively May Increase Risk for Chronic Pain Post-TKR

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Individuals with knee osteoarthritis who have indicators of high vs low/no levels of neuropathic pain may be at elevated risk for chronic pain after total knee replacement surgery.

Positive Phase 3 Results for Novel OA Pain Treatment Tanezumab

Positive Phase 3 Results for Novel OA Pain Treatment Tanezumab

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Pfizer and Lilly announced positive results from a study evaluating tanezumab, an investigational humanized monoclonal antibody, for the treatment of OA pain.

Multiple Factors to Consider When Selecting NSAIDs for Arthritis

Multiple Factors to Consider When Selecting NSAIDs for Arthritis

Factors to be considered when choosing the correct NSAID for arthritis include effectiveness, concurrent health conditions, and frequency of use.

Psychosocial Interventions May Improve Outcomes in Orthopedic Surgery

Psychosocial Interventions May Improve Outcomes in Orthopedic Surgery

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Psychosocial interventions such as patient education and relaxation techniques may help reduce pain after orthopedic surgery and improve quality of clinical care.

Consensus Guidelines for the Use of Intravenous Ketamine for Chronic Pain

Consensus Guidelines for the Use of Intravenous Ketamine for Chronic Pain

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A panel of experts formulated consensus guidelines for physicians who use intravenous ketamine infusions to treat chronic pain.

Increased Rates of Opioid- and Injection Drug Use-Related Septic Knee Arthritis

Increased Rates of Opioid- and Injection Drug Use-Related Septic Knee Arthritis

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The percentage of patients with septic arthritis related to opioid or injection drug use was found to have increased from 2000 to 2013.

Zoledronic Acid May Not Improve Knee Osteoarthritis-Related Pain, Function Long-Term

Zoledronic Acid May Not Improve Knee Osteoarthritis-Related Pain, Function Long-Term

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Zoledronic acid did not significantly reduce knee pain or bone marrow lesion size overall in patients with knee osteoarthritis over 24 months.

Tofacitinib May Effectively Alleviate Pain in RA, Psoriatic Arthritis, and Ankylosing Spondylitis

Tofacitinib May Effectively Alleviate Pain in RA, Psoriatic Arthritis, and Ankylosing Spondylitis

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Tofacitinib may provide a fast and prolonged analgesic effect in patients with rheumatoid arthritis or psoriatic arthritis who are unresponsive to csDMARD or to TNFi, as well as in individuals with ankylosing spondylitis.

Initial High Disease Activity in Rheumatoid Arthritis Linked to Depression

Initial High Disease Activity in Rheumatoid Arthritis Linked to Depression

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Investigators sought to determine whether initial high disease activity or changes in disease activity contribute to the development of persistent depression among patients with early rheumatoid arthritis.

Anesthetic-Loaded Bone Cements May Accelerate Post-Reconstruction Recovery

Anesthetic-Loaded Bone Cements May Accelerate Post-Reconstruction Recovery

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Calcium phosphate cement loaded with bupivacaine vs ropivacaine may accelerate functional recovery after bone reconstruction surgery and maintain bone-filling properties.

Benefit of Liposomal Bupivacaine for Pain in TKA Questioned

Benefit of Liposomal Bupivacaine for Pain in TKA Questioned

Liposomal bupivacaine use in patients undergoing TKA is not associated with clinically meaningful reductions in inpatient opioid use.

Vertebroplasty Comparable With Placebo for Acute Vertebral Compression Fractures

Vertebroplasty Comparable With Placebo for Acute Vertebral Compression Fractures

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Percutaneous vertebroplasty for acute osteoporotic vertebral compression fractures may not provide analgesic benefits superior to a sham procedure.

Regional Anesthesia Tied to Lower Opioid Use in TKA, THA

Regional Anesthesia Tied to Lower Opioid Use in TKA, THA

Regional anesthesia is associated with a lower opioid consumption in both knee and hip replacement surgeries, compared to general anesthesia.

Education Plus Exercise, Single Corticosteroid Injection Effective in Long Term for Gluteal Tendinopathy

Education Plus Exercise, Single Corticosteroid Injection Effective in Long Term for Gluteal Tendinopathy

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Education combined with exercise as well as a single corticosteroid injection may be more effective than a wait-and-see approach for alleviating gluteal tendinopathy-associated pain.

Gluteal Loading Exercise May Not Improve Greater Trochanteric Pain Syndrome

Gluteal Loading Exercise May Not Improve Greater Trochanteric Pain Syndrome

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Adding an exercise regimen to a comprehensive educational program for the management of greater trochanteric pain syndrome may not bring significant benefit.

Pain, Cognitive Dysfunction in SLE Mediated by Sleep Disturbance, Depression

Pain, Cognitive Dysfunction in SLE Mediated by Sleep Disturbance, Depression

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The relationship between pain and cognitive dysfunction was explained by sleep disturbance and depressive symptoms.

Factors Associated With Neuropathic Pain in Ankylosing Spondylitis

Factors Associated With Neuropathic Pain in Ankylosing Spondylitis

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A number of factors that include age, the presence of enthesitis, and depressive symptoms may be associated with neuropathic pain in ankylosing spondylitis.

Influence of Psychosocial, Sociodemographic Factors on Knee Osteoarthritis-Associated Pain

Influence of Psychosocial, Sociodemographic Factors on Knee Osteoarthritis-Associated Pain

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A set of psychosocial and sociodemographic factors may be associated with pain levels in patients with knee osteoarthritis.

Periarticular Injection vs Psoas Block for THA-Associated Postoperative Pain

Periarticular Injection vs Psoas Block for THA-Associated Postoperative Pain

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Intraoperative periarticular local anesthetic infiltration and psoas compartment block may provide comparable analgesia after total hip arthroplasty.

Less Pain After TKA With Addition of Peripheral Nerve Blocks

Less Pain After TKA With Addition of Peripheral Nerve Blocks

Addition of an interspace between the popliteal artery and capsule of the posterior knee block and adductor canal block to periarticular injection is associated with less pain after TKA.

Femoral Nerve Block Alone or in Combination With Sciatic Nerve Block for TKA: A Meta-Analysis

Femoral Nerve Block Alone or in Combination With Sciatic Nerve Block for TKA: A Meta-Analysis

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Sciatic nerve block may represent an effective complement to femoral nerve block for total knee arthroplasty.

Intramuscular Triamcinolone Acetate Injection for OA Hip Pain

Intramuscular Triamcinolone Acetate Injection for OA Hip Pain

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In patients with painful hip osteoarthritis, an intramuscular glucocorticoid injection may effectively alleviate hip pain in the short-term.

Corticosteroids May Be an Effective Alternative to NSAIDs in Acute Gout Pain

Corticosteroids May Be an Effective Alternative to NSAIDs in Acute Gout Pain

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Corticosteroids appear to be a reasonable alternative to NSAIDs for the treatment of acute pain as a result of gout.

Multimodal Analgesia After Knee, Hip Arthroplasty and Perioperative Outcomes

Multimodal Analgesia After Knee, Hip Arthroplasty and Perioperative Outcomes

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Multimodal analgesia after hip or knee arthroplasty may be associated with fewer complications and reduced opioid prescriptions and hospital length of stay, compared with unimodal analgesia.

Radiofrequency Ablation for Chronic Hip Pain in Osteoarthritis: Reviewing the Evidence

Radiofrequency Ablation for Chronic Hip Pain in Osteoarthritis: Reviewing the Evidence

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The available evidence suggests that radiofrequency ablation is a feasible treatment option for chronic hip pain associated with degenerative diseases.

Subcutaneous vs Intravenous Tanezumab for Knee, Hip Osteoarthritis

Subcutaneous vs Intravenous Tanezumab for Knee, Hip Osteoarthritis

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Intravenous and subcutaneous administration of tanezumab may provide similar analgesia and tolerability in patients with hip or knee osteoarthritis.

Catastrophizing, Fibromyalgia, and the Cognitive Modulation of Pain

Catastrophizing, Fibromyalgia, and the Cognitive Modulation of Pain

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Pain catastrophizing may be associated with a reduced ability to effectively distract the mind from pain in patients with fibromyalgia.

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