Pain Management

Internet-Delivered Exposure Therapy Cost-Effective for Patients With Fibromyalgia

Internet-Delivered Exposure Therapy Cost-Effective for Patients With Fibromyalgia

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In a randomized control trial, researchers found that internet-delivered exposure therapy was more cost-effective for patients with fibromyalgia than a waitlist control, which did not involve any treatment during the experimental phase of the study.

Utility of Repeated Sacroiliac Joint MRI in Chronic Back Pain, Suspected axSpA

Utility of Repeated Sacroiliac Joint MRI in Chronic Back Pain, Suspected axSpA

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Findings suggest that repeating MRI of the sacroiliac joints after 3 months or 1 year in patients with chronic back pain and suspected axial spondyloarthritis was not useful.

Inflammatory Back Pain Resolves in Many Patients

Inflammatory Back Pain Resolves in Many Patients

Inflammatory back pain often resolves, while in 30% of patients it progresses to spondyloarthritis within 10 years.

Pain Severity May Partly Mediate the Association Between Depression and Physical Performance in Knee OA

Pain Severity May Partly Mediate the Association Between Depression and Physical Performance in Knee OA

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Pain may partly mediate the observed association between physical performance and depressive symptoms in patients with radiographic knee osteoarthritis.

Rheumatologist-Assessed vs Criteria for Inflammatory Back Pain in Psoriatic Arthritis

Rheumatologist-Assessed vs Criteria for Inflammatory Back Pain in Psoriatic Arthritis

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Rheumatologist-assessed inflammatory back pain (IBP) or the criteria for IBP developed for ankylosing spondylitis might not perform well when determining axial involvement in psoriatic arthritis.

Effects of Statin Use on Pain Outcomes in Knee Osteoarthritis

Effects of Statin Use on Pain Outcomes in Knee Osteoarthritis

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Individuals using statins over 5 years and those using atorvastatin reported a lower risk for future osteoarthritis-related knee pain.

Combining Hyaluronic Acid With Platelet-Rich Plasma Injections for Primary Knee Osteoarthritis

Combining Hyaluronic Acid With Platelet-Rich Plasma Injections for Primary Knee Osteoarthritis

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Hyaluronic acid therapy may be more effective when supplemented with intra-articular platelet-rich plasma injections vs alone in treating primary knee osteoarthritis.

Effects of Pain, Depression, and Insomnia on Health Care Use in Older Adults With Osteoarthritis

Effects of Pain, Depression, and Insomnia on Health Care Use in Older Adults With Osteoarthritis

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The combined effects of pain with insomnia and pain with depression increased diverse types of health care use.

Decreased Pain May Mediate Effects of Soft Knee Brace on Activity Limitations in Knee OA

Decreased Pain May Mediate Effects of Soft Knee Brace on Activity Limitations in Knee OA

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A decrease of pain and a decrease of dynamic knee instability mediated the effect of wearing a soft knee brace on reduction of activity limitations.

Inflammatory Back Pain and Neuropathic Pain May Affect Axial Spondyloarthritis Outcomes

Inflammatory Back Pain and Neuropathic Pain May Affect Axial Spondyloarthritis Outcomes

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Patients with axial spondyloarthritis who have inflammatory back pain or neuropathic pain may have higher pain intensity, pain interference, disease activity, and greater functional limitation compared with individuals with axial spondyloarthritis but without either comorbidity.

Opioid Use in Osteoarthritis Linked to Worse Pain Interference, Functioning

Opioid Use in Osteoarthritis Linked to Worse Pain Interference, Functioning

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In patients with osteoarthritis, chronic pain is a primary symptom that may limit daily activities and impair function.

Radiographic Changes of Osteoarthritis Associated With Persistent Knee Pain

Radiographic Changes of Osteoarthritis Associated With Persistent Knee Pain

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Researchers examined the correlation between knee pain and radiographic features of osteoarthritis.

Hip Injury and "Giving Way" Associated With Pain Exacerbation in Hip Osteoarthritis

Hip Injury and "Giving Way" Associated With Pain Exacerbation in Hip Osteoarthritis

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Buckling of the hip joint, also referred to as "giving way," and hip injuries may be associated with hip pain worsening in patients with symptomatic hip osteoarthritis.

Pain Scores After Total Knee Arthroplasty May Predict Chronic Opioid Use

Pain Scores After Total Knee Arthroplasty May Predict Chronic Opioid Use

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Acute postoperative pain scores were found to be associated with chronic opioid use after total knee arthroplasty in patients taking opioid medications prior to intervention.

Knee Load Associated With Increased Walking Pain in Osteoarthritis

Knee Load Associated With Increased Walking Pain in Osteoarthritis

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Researchers examine the association between the knee adduction moment and increased knee pain during walking in patients with knee osteoarthritis.

Widespread Pain Common, Linked to Worse Patient-Reported Disease Activity in PsA

Widespread Pain Common, Linked to Worse Patient-Reported Disease Activity in PsA

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Widespread nonarthritic pain is linked to worse patient-reported and composite psoriatic arthritis activity measures.

Endocannabinoids May Be Elevated in Women With Fibromyalgia

Endocannabinoids May Be Elevated in Women With Fibromyalgia

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Women with fibromyalgia were found to have elevated levels of endocannabinoidome lipid mediators.

Higher PainDETECT Scores, Neuropathic Pain Preoperatively May Increase Risk for Chronic Pain Post-TKR

Higher PainDETECT Scores, Neuropathic Pain Preoperatively May Increase Risk for Chronic Pain Post-TKR

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Individuals with knee osteoarthritis who have indicators of high vs low/no levels of neuropathic pain may be at elevated risk for chronic pain after total knee replacement surgery.

Positive Phase 3 Results for Novel OA Pain Treatment Tanezumab

Positive Phase 3 Results for Novel OA Pain Treatment Tanezumab

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Pfizer and Lilly announced positive results from a study evaluating tanezumab, an investigational humanized monoclonal antibody, for the treatment of OA pain.

Multiple Factors to Consider When Selecting NSAIDs for Arthritis

Multiple Factors to Consider When Selecting NSAIDs for Arthritis

Factors to be considered when choosing the correct NSAID for arthritis include effectiveness, concurrent health conditions, and frequency of use.

Psychosocial Interventions May Improve Outcomes in Orthopedic Surgery

Psychosocial Interventions May Improve Outcomes in Orthopedic Surgery

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Psychosocial interventions such as patient education and relaxation techniques may help reduce pain after orthopedic surgery and improve quality of clinical care.

Consensus Guidelines for the Use of Intravenous Ketamine for Chronic Pain

Consensus Guidelines for the Use of Intravenous Ketamine for Chronic Pain

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A panel of experts formulated consensus guidelines for physicians who use intravenous ketamine infusions to treat chronic pain.

Increased Rates of Opioid- and Injection Drug Use-Related Septic Knee Arthritis

Increased Rates of Opioid- and Injection Drug Use-Related Septic Knee Arthritis

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The percentage of patients with septic arthritis related to opioid or injection drug use was found to have increased from 2000 to 2013.

Zoledronic Acid May Not Improve Knee Osteoarthritis-Related Pain, Function Long-Term

Zoledronic Acid May Not Improve Knee Osteoarthritis-Related Pain, Function Long-Term

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Zoledronic acid did not significantly reduce knee pain or bone marrow lesion size overall in patients with knee osteoarthritis over 24 months.

Tofacitinib May Effectively Alleviate Pain in RA, Psoriatic Arthritis, and Ankylosing Spondylitis

Tofacitinib May Effectively Alleviate Pain in RA, Psoriatic Arthritis, and Ankylosing Spondylitis

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Tofacitinib may provide a fast and prolonged analgesic effect in patients with rheumatoid arthritis or psoriatic arthritis who are unresponsive to csDMARD or to TNFi, as well as in individuals with ankylosing spondylitis.

Initial High Disease Activity in Rheumatoid Arthritis Linked to Depression

Initial High Disease Activity in Rheumatoid Arthritis Linked to Depression

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Investigators sought to determine whether initial high disease activity or changes in disease activity contribute to the development of persistent depression among patients with early rheumatoid arthritis.

Anesthetic-Loaded Bone Cements May Accelerate Post-Reconstruction Recovery

Anesthetic-Loaded Bone Cements May Accelerate Post-Reconstruction Recovery

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Calcium phosphate cement loaded with bupivacaine vs ropivacaine may accelerate functional recovery after bone reconstruction surgery and maintain bone-filling properties.

Benefit of Liposomal Bupivacaine for Pain in TKA Questioned

Benefit of Liposomal Bupivacaine for Pain in TKA Questioned

Liposomal bupivacaine use in patients undergoing TKA is not associated with clinically meaningful reductions in inpatient opioid use.

Vertebroplasty Comparable With Placebo for Acute Vertebral Compression Fractures

Vertebroplasty Comparable With Placebo for Acute Vertebral Compression Fractures

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Percutaneous vertebroplasty for acute osteoporotic vertebral compression fractures may not provide analgesic benefits superior to a sham procedure.

Regional Anesthesia Tied to Lower Opioid Use in TKA, THA

Regional Anesthesia Tied to Lower Opioid Use in TKA, THA

Regional anesthesia is associated with a lower opioid consumption in both knee and hip replacement surgeries, compared to general anesthesia.

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