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Managing Uveitis in Juvenile Idiopathic Arthritis: Consensus-Based Recommendations

Managing Uveitis in Juvenile Idiopathic Arthritis: Consensus-Based Recommendations

The SHARE initiative has provided recommendations for the diagnosis and treatment of juvenile idiopathic arthritis-associated uveitis.

Clinical Features Identified in Enthesitis-Related Juvenile Idiopathic Arthritis, Juvenile Spondyloarthritis

Clinical Features Identified in Enthesitis-Related Juvenile Idiopathic Arthritis, Juvenile Spondyloarthritis

Results confirm that juvenile spondyloarthritis is characterized by its peripheral pattern at disease onset, with peripheral arthritis and enthesitis.

Genetic Risk Loci Found Within Disease Phenotypes Including SLE, JIA

Genetic Risk Loci Found Within Disease Phenotypes Including SLE, JIA

The Epstein-Barr virus EBNA2 protein and many coclustering human transcription factors occupied nearly half of SLE risk loci.

Ultrasound Not Predictive of Disease Flares for Inactive Juvenile Idiopathic Arthritis

Ultrasound Not Predictive of Disease Flares for Inactive Juvenile Idiopathic Arthritis

Abnormal ultrasound findings were common in patients with juvenile idiopathic arthritis with clinically inactive disease.

Flare Risk Examined in Juvenile Idiopathic Arthritis After Anti-TNF Therapy Discontinuation

Flare Risk Examined in Juvenile Idiopathic Arthritis After Anti-TNF Therapy Discontinuation

Researchers sought to determine the predictors of disease flare after anti-TNF therapy discontinuation in children with polyarticular forms of juvenile idiopathic arthritis with sustained clinically inactive disease.

Examining the Role of Neutrophils in Systemic-Onset Juvenile Idiopathic Arthritis

Examining the Role of Neutrophils in Systemic-Onset Juvenile Idiopathic Arthritis

High neutrophil counts decreased after initiation of recombinant interleukin-1 receptor agonist therapy in systemic-onset juvenile idiopathic arthritis.

Childhood-Onset SLE Often Results in Damage to Several Organ Systems

Childhood-Onset SLE Often Results in Damage to Several Organ Systems

Disease damage in patients with childhood-onset SLE is common, even with relatively short disease durations.

TNF Inhibitor Therapy Unlikely to Affect Malignancy Risk in Children

TNF Inhibitor Therapy Unlikely to Affect Malignancy Risk in Children

Children with juvenile idiopathic arthritis, pediatric inflammatory bowel disease, and pediatric plaque psoriasis had an increased incidence of childhood malignancies, regardless of TNFi exposure.

Juvenile Idiopathic Arthritis: Baseline Ultrasound Abnormalities May Predict Relapse

Juvenile Idiopathic Arthritis: Baseline Ultrasound Abnormalities May Predict Relapse

Abnormality on an ultrasound examination significantly increased the risk for flare in patients with juvenile idiopathic arthritis.

Predictors of Disability Assessed in Childhood-Onset Systemic Lupus Erythematosus

Predictors of Disability Assessed in Childhood-Onset Systemic Lupus Erythematosus

Data from the CARRA Legacy Registry show disability is common in patients with childhood-onset SLE.

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