Pediatric Rheumatology

Juvenile Idiopathic Arthritis: Baseline Ultrasound Abnormalities May Predict Relapse

Juvenile Idiopathic Arthritis: Baseline Ultrasound Abnormalities May Predict Relapse

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Abnormality on an ultrasound examination significantly increased the risk for flare in patients with juvenile idiopathic arthritis.

Predictors of Disability Assessed in Childhood-Onset Systemic Lupus Erythematosus

Predictors of Disability Assessed in Childhood-Onset Systemic Lupus Erythematosus

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Data from the CARRA Legacy Registry show disability is common in patients with childhood-onset SLE.

Improving Pediatric Rheumatic Disease Care With Consensus-Based Treatment Plans

Improving Pediatric Rheumatic Disease Care With Consensus-Based Treatment Plans

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The goal of consensus treatment plans is to drive a cycle of innovation and replacement that allows the addition of new treatments and the removal of unused or ineffective strategies.

Rheumatoid Arthritis Exposure In Utero Increases Chronic Disease Risk in Children

Rheumatoid Arthritis Exposure In Utero Increases Chronic Disease Risk in Children

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Maternal RA exposure in utero may increase the risk for certain chronic conditions, including RA, thyroid disease, and epilepsy.

More Severe Disease Found in Juvenile Myositis With Anti-NT5C1A Autoantibodies

More Severe Disease Found in Juvenile Myositis With Anti-NT5C1A Autoantibodies

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Autoantibodies that recognize cytosolic 5′-nucleotidase 1A were detected in about 25% of patients with juvenile myositis and juvenile idiopathic arthritis.

Choosing a Biologic Therapy for JIA: Etanercept vs Tocilizumab vs IL-1 Inhibitors

Choosing a Biologic Therapy for JIA: Etanercept vs Tocilizumab vs IL-1 Inhibitors

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Treatment response was most significant in patients taking either tocilizumab or an interleukin-1 inhibitor.

Inhaled Corticosteroid Use Not Associated With Fracture Risk in Pediatric Patients

Inhaled Corticosteroid Use Not Associated With Fracture Risk in Pediatric Patients

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Systemic but not inhaled corticosteroid use may be associated with increased fracture risk in pediatric patients.

Fluorescence Optical Imaging for Diagnosis of Pediatric Rheumatologic Conditions

Fluorescence Optical Imaging for Diagnosis of Pediatric Rheumatologic Conditions

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Chronic inflammatory rheumatologic diseases benefit from early anti-inflammatory treatment; however, interdisciplinary approaches may be necessary for identifying and managing noninflammatory joint pain.

Clinical Juvenile Arthritis Disease Activity Score Use in Treat-to-Target Therapy

Clinical Juvenile Arthritis Disease Activity Score Use in Treat-to-Target Therapy

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The objective of this study is to determine whether the JADAS or cJADAS would accurately predict patients with JIA in need of treatment escalation to anti-TNF after starting MTX.

Internet Intervention Improves Pain, QoL in Juvenile Idiopathic Arthritis

Internet Intervention Improves Pain, QoL in Juvenile Idiopathic Arthritis

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Psychoeducational treatments can aid in the transition to adult care, but this is often lacking for teens due to access issues.

Anti-Tumor Necrosis Factor Agents vs csDMARDs for Pediatric Enthesitis-Related Arthritis

Anti-Tumor Necrosis Factor Agents vs csDMARDs for Pediatric Enthesitis-Related Arthritis

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In children with enthesitis-related arthritis, the use of anti-tumor necrosis factor (TNF) agents within the first year of diagnosis has demonstrated benefits in several clinically meaningful outcomes.

Juvenile Idiopathic Arthritis Treated With Biologic Therapy: Risk Factors for Infection

Juvenile Idiopathic Arthritis Treated With Biologic Therapy: Risk Factors for Infection

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Patients with juvenile idiopathic arthritis under biologic therapy in a real-world setting have high rates of serious infections.

Femoral Stress Index is Associated with Fracture Risk in School Age Children

Femoral Stress Index is Associated with Fracture Risk in School Age Children

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The FSI proved to be at least as effective in predicting fracture risk in children as femoral and total body BMD.

New Assessment Tool Predicts Pediatric Fracture Risk

New Assessment Tool Predicts Pediatric Fracture Risk

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A new bone assessment evaluates fracture risk in children.

Juvenile Idiopathic Arthritis Increases Risk of Postpartum Complications

Juvenile Idiopathic Arthritis Increases Risk of Postpartum Complications

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Ongoing inflammation related to JIA may put first-time mothers at risk for complications.

Cardiovascular Risks in JIA Linked to Serum Vitamin D Level

Cardiovascular Risks in JIA Linked to Serum Vitamin D Level

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Thirty controls were compared with 30 patients with juvenile idiopathic arthritis to determine the link between vitamin D and CVD.

Diffuse Alveolar Hemorrhage in SLE Associated With Serious Disease Flare

Diffuse Alveolar Hemorrhage in SLE Associated With Serious Disease Flare

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This condition is associated with serious disease flare complicated by sepsis and a high mortality rate.

ANG-2 as Disease Marker in Children With Juvenile Idiopathic Arthritis

ANG-2 as Disease Marker in Children With Juvenile Idiopathic Arthritis

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When combined with ultrasound examination, ANG-2 can help lead to the appropriate therapy for JIA.

Diagnosing Pediatric Lyme Arthritis

Diagnosing Pediatric Lyme Arthritis

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Children are some of the most susceptible to Lyme disease. In many children, joint inflammation may be the first symptom.

Pediatric Residents Experiencing a High Level of Burnout

Pediatric Residents Experiencing a High Level of Burnout

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Study surveyed 258 residents from 11 pediatric residency programs to assess the prevalence of burnout.

Juvenile Arthritis with Sleep Apnea Impairs Neurobehavioral Performance

Juvenile Arthritis with Sleep Apnea Impairs Neurobehavioral Performance

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Study examines children with juvenile idiopathic arthritis who underwent overnight polysomnography and neurobehavioral assessments.

Juvenile Dermatomyositis Management Recommendations Established

Juvenile Dermatomyositis Management Recommendations Established

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A European committee of pediatric rheumatology experts has provided the first consensus-based recommendations for clinical management of juvenile dermatomyositis.

Juvenile Fibromyalgia Pain Treatment Enhanced By Psychosocial Impact Therapies

Juvenile Fibromyalgia Pain Treatment Enhanced By Psychosocial Impact Therapies

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Novel psychosocial therapies such as cognitive behavioral therapy that have been effective in adults with fibromyalgia need additional neuromuscular fitness training to overcome catastrophizing and fear of exercise in adolescents.

Effects of Depression in Children With Chronic Pain

Effects of Depression in Children With Chronic Pain

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Study suggests that functioning and pain interference should be routinely assessed in children with chronic pain.

Lupus Research Grants Available for Post-Graduate Study

Lupus Research Grants Available for Post-Graduate Study

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The Lupus Foundation of America is now accepting applications for 8 grants, with dedicated awards to minority applicants, pediatric research, and research that has an impact on rural areas.

Emerging Research in Pediatric Localized Scleroderma

Emerging Research in Pediatric Localized Scleroderma

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Sarah Taber, MD, briefly reviews her ongoing research on genetic drivers of localized scleroderma in pediatric patients.

ADA Dosed Weekly Safe in Pediatric JIA, Chronic Uveitis

ADA Dosed Weekly Safe in Pediatric JIA, Chronic Uveitis

Most commonly used to treat chronic uveitis, weekly adalimumab was linked to a positive clinical response in 93% of patients.

Evaluation of the Pediatric Patient With Joint Pain and Swelling

Evaluation of the Pediatric Patient With Joint Pain and Swelling

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Watch a video providing a comprehensive review of the distinguishing factors between the presentation of septic arthritis and Lyme arthritis.

Novel Urinary Biomarker Index to Noninvasively Assess LN

Novel Urinary Biomarker Index to Noninvasively Assess LN

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The Renal Activity Index for Lupus (RAIL) was developed by researchers utilizing urinary biomarkers of LN as a way non-invasively assess degrees of LN inflammation.

Air Particulate Exposure Associated With Pediatric Lupus Activity

Air Particulate Exposure Associated With Pediatric Lupus Activity

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Exposure to certain fine particulate matter in air pollution was associated with increased severity of lupus disease activity in pediatric patients

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