There is an unmet need for mental health interventions that address illness-related issues affecting youth with rheumatologic conditions.
Health professionals from many disciplines need to be able to recognize the clinical presentations, essential diagnostic tests, and treatment approach of Lyme neuroborreliosis.
Low nailfold capillary density is associated with impaired pulmonary function tests and more frequent high-resolution computed tomography abnormalities in patients with juvenile dermatomyositis.
The JDM Image Score may have the potential to serve as a reliable biomarker of disease severity and response to therapeutic interventions in children with juvenile dermatomyositis.
Prediction models of outcomes in juvenile idiopathic arthritis have acceptable precision and require only readily available baseline variables.
The investigators sought to evaluate the time patients were in remission after discontinuing biologic therapy for the treatment of JIA.
The FDA has approved the subcutaneous formulation of Actemra for the treatment of active polyarticular juvenile idiopathic arthritis.
Baseline depressive symptoms were associated with pain and disability in adolescents with juvenile idiopathic arthritis.
Researchers evaluated the safety and efficacy of adalimumab and infliximab in the treatment of juvenile idiopathic arthritis-associated uveitis in patients treated for at least 2 years.
Researchers sought to include Doppler findings in the evaluation and definition of normal joint features that can be visualized in healthy children in different age groups.
Investigators aimed to examine the use of treatment targets in juvenile idiopathic arthritis in terms of joint limitations, functional ability, psychosocial health, and pain levels.
The SHARE initiative has provided recommendations for the diagnosis and treatment of juvenile idiopathic arthritis-associated uveitis.
Clinical Features Identified in Enthesitis-Related Juvenile Idiopathic Arthritis, Juvenile SpondyloarthritisApril 20, 2018
Results confirm that juvenile spondyloarthritis is characterized by its peripheral pattern at disease onset, with peripheral arthritis and enthesitis.
Abnormal ultrasound findings were common in patients with juvenile idiopathic arthritis with clinically inactive disease.
Researchers sought to determine the predictors of disease flare after anti-TNF therapy discontinuation in children with polyarticular forms of juvenile idiopathic arthritis with sustained clinically inactive disease.
High neutrophil counts decreased after initiation of recombinant interleukin-1 receptor agonist therapy in systemic-onset juvenile idiopathic arthritis.
Disease damage in patients with childhood-onset SLE is common, even with relatively short disease durations.
Children with juvenile idiopathic arthritis, pediatric inflammatory bowel disease, and pediatric plaque psoriasis had an increased incidence of childhood malignancies, regardless of TNFi exposure.
Abnormality on an ultrasound examination significantly increased the risk for flare in patients with juvenile idiopathic arthritis.
Data from the CARRA Legacy Registry show disability is common in patients with childhood-onset SLE.
The goal of consensus treatment plans is to drive a cycle of innovation and replacement that allows the addition of new treatments and the removal of unused or ineffective strategies.
Maternal RA exposure in utero may increase the risk for certain chronic conditions, including RA, thyroid disease, and epilepsy.
Autoantibodies that recognize cytosolic 5′-nucleotidase 1A were detected in about 25% of patients with juvenile myositis and juvenile idiopathic arthritis.
Treatment response was most significant in patients taking either tocilizumab or an interleukin-1 inhibitor.
Systemic but not inhaled corticosteroid use may be associated with increased fracture risk in pediatric patients.
Chronic inflammatory rheumatologic diseases benefit from early anti-inflammatory treatment; however, interdisciplinary approaches may be necessary for identifying and managing noninflammatory joint pain.
The objective of this study is to determine whether the JADAS or cJADAS would accurately predict patients with JIA in need of treatment escalation to anti-TNF after starting MTX.
Psychoeducational treatments can aid in the transition to adult care, but this is often lacking for teens due to access issues.
In children with enthesitis-related arthritis, the use of anti-tumor necrosis factor (TNF) agents within the first year of diagnosis has demonstrated benefits in several clinically meaningful outcomes.
Patients with juvenile idiopathic arthritis under biologic therapy in a real-world setting have high rates of serious infections.
Rheumatology Advisor Articles
- Promising Antibody Markers Identified for aPL-Related Pregnancy Complications
- Comorbid Fibromyalgia Influences Disease Activity, Quality of Life in Axial Spondyloarthritis
- Efficacy of ABT-122 Maintained in Psoriatic Arthritis, Rheumatoid Arthritis at 36 Weeks
- Knee Load Associated With Increased Walking Pain in Osteoarthritis
- Pain Catastrophizing Decreases in Rheumatoid Arthritis After DMARD Initiation
- Genetic Screening May Predict Osteoporosis, Fracture Risk
- Exploring the Clinical Implications of Cannabinoid Use in Rheumatoid Arthritis
- Diagnosing Lyme Disease in Children With Neuropsychiatric Illness
- Predicting Primary Nonresponse to Methotrexate in Rheumatoid Arthritis
- Prednisone, Prednisolone Does Not Adversely Affect Bone Mineral Density in RA
- Characteristics of Early-Onset SLE Distinguished From Mimicking Conditions
- Uric Acid Predicts AKI Risk After Cardiac Surgery
- Examining Gaps in Mental Health Care Among Youth With Juvenile Rheumatic Disease
- AMA Proposes Policy Opposing Medicaid 'Lockout' Provisions
- TNFi Not Linked to Increased Risk for Cancer Recurrence in Rheumatoid Arthritis