PodCasts Archive - Rheumatology Advisor

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Podcast: Bone Resorption: a Manifestation of RA Mediated by Elevated IL-6

The content contained in this podcast was jointly developed by Dr. Robin Dore and Sanofi Genzyme RA is associated with systemic bone remodeling leading to bone loss. Under normal conditions, proinflammatory cytokines, including IL-6, regulate bone remodeling. However, in patients with RA, IL-6 promotes bone resorption. IL-6 contributes to bone resorption by stimulating RANKL expression…