Rheumatoid Arthritis

Yoga May Help With Rheumatoid Arthritis Symptoms, Severity

Yoga May Help With Rheumatoid Arthritis Symptoms, Severity

Yoga may be effective as a complementary or adjunct therapy for patients with rheumatoid arthritis taking disease-modifying antirheumatic drugs.

Effectiveness of Biologic DMARDs in Rheumatoid Arthritis Compared

Effectiveness of Biologic DMARDs in Rheumatoid Arthritis Compared

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Researchers compared the real-world absolute and relative effectiveness in patients with RA of starting any of the available biologic DMARDs.

Predictors of Treatment Adherence Assessed in Rheumatic Diseases

Predictors of Treatment Adherence Assessed in Rheumatic Diseases

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Medication adherence in rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis was affected more by treated beliefs compared with disease-related factors.

Clinical, Radiographic Benefits of Tofacitinib Sustained for 2 Years in Rheumatoid Arthritis

Clinical, Radiographic Benefits of Tofacitinib Sustained for 2 Years in Rheumatoid Arthritis

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Clinical and radiographic treatment effects were sustained through 24 months in patients with RA receiving tofacitinib.

Baricitinib Therapy in RA Not Associated With Adverse Cardiovascular Events

Baricitinib Therapy in RA Not Associated With Adverse Cardiovascular Events

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Investigators pooled data from 9 RA clinical trials to examine the frequency of certain adverse events associated with baricitinib treatment for RA.

5 Best Apps for Rheumatoid Arthritis

5 Best Apps for Rheumatoid Arthritis

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A number of smartphone apps may help your patients manage their rheumatoid arthritis. We list the 5 best in 2019.

Periarticular Bone Loss Inhibition Linked to Clinical Remission in RA

Periarticular Bone Loss Inhibition Linked to Clinical Remission in RA

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Investigators examined the relationship between metacarpal bone mineral density, as assessed by digital x-ray radiogrammetry, and clinical remission and ACR70 response in patients with rheumatoid arthritis treated with certolizumab pegol.

Contraception Use Evaluated in Women With Rheumatoid Arthritis, Psoriatic Arthritis

Contraception Use Evaluated in Women With Rheumatoid Arthritis, Psoriatic Arthritis

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However, women with PsA were less likely to use any form of contraceptive compared with women with RA.

No Benefit for MRI-Guided Treat-to-Target Strategy in Rheumatoid Arthritis

No Benefit for MRI-Guided Treat-to-Target Strategy in Rheumatoid Arthritis

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Data do not support the use of an MRI-guided treat-to-target strategy for treating patients with rheumatoid arthritis.

Longitudinal TNF Levels Mainly Stable With Adalimumab in RA

Longitudinal TNF Levels Mainly Stable With Adalimumab in RA

For patients with RA, longitudinal TNF concentrations are mainly stable during adalimumab treatment, although early low TNF is strongly linked to nonresponse to treatment.

TNFi Discontinuation During Early Pregnancy Not Linked With Worse RA, JIA Outcomes

TNFi Discontinuation During Early Pregnancy Not Linked With Worse RA, JIA Outcomes

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Discontinuing TNFi therapy before 20 weeks gestation was feasible in wo\men with RA and JIA who enter pregnancy with well-controlled disease.

Vitamin D, Calcium May Improve BMD in Postmenopausal Women With RA, Osteoporosis

Vitamin D, Calcium May Improve BMD in Postmenopausal Women With RA, Osteoporosis

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Bone mineral density measures were significantly greater at 3 years in postmenopausal women with comorbid osteoporosis and rheumatoid arthritis who were given vitamin D and calcium supplementation.

Fish Intake May Not Protect Against Rheumatoid Arthritis

Fish Intake May Not Protect Against Rheumatoid Arthritis

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Dietary intake of fish did not have a protective effect against rheumatoid arthritis.

No Clinically Meaningful Safety Differences Between Sarilumab, Tocilizumab in RA

No Clinically Meaningful Safety Differences Between Sarilumab, Tocilizumab in RA

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Sarilumab and tocilizumab have shown no clinically relevant differences in safety and tolerability outcomes.

Biologic Therapies in JIA: International Registry Data Combined

Biologic Therapies in JIA: International Registry Data Combined

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National and international pharmacovigilance registry data pertaining to the use of biologic agents in patients with juvenile idiopathic arthritis have been combined.

Vitamin D Deficiency Linked to Uveitis, Disease Activity in Juvenile Idiopathic Arthritis

Vitamin D Deficiency Linked to Uveitis, Disease Activity in Juvenile Idiopathic Arthritis

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Vitamin D deficiency was common and associated with higher disease activity and risk for juvenile idiopathic arthritis-associated uveitis.

Tender Joint Count May Not Reflect Inflammation Activity in Rheumatoid Arthritis

Tender Joint Count May Not Reflect Inflammation Activity in Rheumatoid Arthritis

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The inclusion of tender joint count in the Composite Disease Activity Score may contribute to misleading information about inflammatory activity.

Increased Risk for Cancer Observed in Abatacept-Treated Rheumatoid Arthritis

Increased Risk for Cancer Observed in Abatacept-Treated Rheumatoid Arthritis

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The use of abatacept as an initial bDMARD for the treatment of patients with rheumatoid arthritis is associated with a slightly elevated risk for cancer overall.

Evaluating Associations of Financial Conflicts of Interest With RA Drug Trial Outcomes

Evaluating Associations of Financial Conflicts of Interest With RA Drug Trial Outcomes

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Researchers examined the prevalence, types, and temporal trends of financial conflicts of interest among authors of drug therapy randomized controlled trials for RA.

Inflammation:  Is It the Link Between Rheumatoid Arthritis and Depression?

Inflammation: Is It the Link Between Rheumatoid Arthritis and Depression?

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Both depression and rheumatoid arthritis contribute substantially to global disability, and these diseases often co-occur.

Increased Prevalence of RA-Related Interstitial Lung Disease Noted in the United States

Increased Prevalence of RA-Related Interstitial Lung Disease Noted in the United States

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The prevalence of rheumatoid arthritis-related interstitial lung disease has increased over the 10-year period from 2004 to 2013.

NDA Submitted for Investigational Rheumatoid Arthritis Treatment

NDA Submitted for Investigational Rheumatoid Arthritis Treatment

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AbbVie has submitted a New Drug Application to the FDA for upadacitinib, their investigational oral treatment for rheumatoid arthritis.

RA Flare Risk Not Predicted by Adalimumab Trough, Antibody Levels

RA Flare Risk Not Predicted by Adalimumab Trough, Antibody Levels

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Flare risk within the year after adalimumab discontinuation was not predicted by trough or antibody levels.

Phone-Based Intervention Aids Rheumatoid Arthritis Care

Phone-Based Intervention Aids Rheumatoid Arthritis Care

A nurse-based phone education intervention can promote shared decision making in patients with newly diagnosed rheumatoid arthritis.

BLA Submitted for Biosimilar Candidate to Remicade

BLA Submitted for Biosimilar Candidate to Remicade

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Amgen has submitted a Biologics License Application (BLA) for ABP 710, a biosimilar to infliximab (Remicade).

Gene Polymorphisms Predict Response to Tocilizumab, Rituximab in RA

Gene Polymorphisms Predict Response to Tocilizumab, Rituximab in RA

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The presence of the FCGR2A rs1801274-TT genotype and FCGR3A rs396991-G allele may act as significant predictors of response to tocilizumab and rituximab therapy in RA.

Elderly Patients Underrepresented in Clinical Trials for Rheumatoid Arthritis, Osteoarthritis

Elderly Patients Underrepresented in Clinical Trials for Rheumatoid Arthritis, Osteoarthritis

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Data show that the elderly are underrepresented in randomized clinical trials for rheumatoid arthritis and osteoarthritis.

Improving RA Diagnosis With Use of Anti-ACPAs

Improving RA Diagnosis With Use of Anti-ACPAs

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In patients with rheumatoid arthritis, the use of multiple antibody assays may improve clinical diagnosis and disease management.

Ultrasound May Be Reliable for Assessing Subtalar Joint Synovitis in Rheumatoid Arthritis

Ultrasound May Be Reliable for Assessing Subtalar Joint Synovitis in Rheumatoid Arthritis

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Data show that ultrasound is a reliable means of evaluating subtalar joint synovitis in patients with rheumatoid arthritis.

Bone Erosions More Frequent With Old Age at Onset of Early RA

Bone Erosions More Frequent With Old Age at Onset of Early RA

Old age at onset of early rheumatoid arthritis is associated with more frequent bone erosions.

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