Investigators sought to determine whether the use of dipeptidyl peptidase-4 inhibitors is associated with the incidence of rheumatoid arthritis.
There is an unmet need for mental health interventions that address illness-related issues affecting youth with rheumatologic conditions.
ABT-122 demonstrated acceptable tolerability and maintenance of efficacy at 36 weeks in patients with RA or PsA receiving background methotrexate.
Patients with RA, particularly elderly patients, who receive the influenza vaccine have significantly lower morbidity and mortality.
The scoring method allows detection of small cortical interruptions on HR-pQCT imaging of finger joints.
Patients who continued or switched their TNF inhibitor after a serious infection had a lower risk for recurrent infection compared with those who stopped the drug.
Researchers sought to characterize patients with rheumatoid arthritis by the number of poor prognostic factors and evaluate treatment acceleration, clinical outcomes, and work status.
Disease activity in patients with rheumatoid arthritis and access to bDMARD care varies across countries worldwide.
Depression screening and management should be incorporated into routine clinical care of patients with RA to reduce pain and functional limitations, improve quality of life, and lower healthcare costs.
A direct recommendation from physicians had the greatest effect on patients' positive vaccination status.
PROMIS measures can detect changes in symptoms of global health, pain, sleep, fatigue, and emotional health in patients with rheumatoid arthritis who are initiating DMARD therapy.
A clear difference exists in the utility of patient-reported measures of disease activity in women with SLE and those with RA.
Health-related quality of life was similar in patients with rheumatoid arthritis and psoriatic arthritis.
The case involved a 68-year-old female patient with rheumatoid arthritis on methotrexate 10 mg weekly who presented to the emergency department with complaints of lethargy and weakness after being prescribed a 2-week course of trimethoprim-sulfamethoxazole for a bacterial skin infection.
Fatigue had a significant and independent effect on work disability measures in rheumatoid arthritis and ankylosing spondylitis.
Many patients with rheumatoid arthritis currently experience missed opportunities to be vaccinated against influenza.
Investigators analyzed MDHAQ/RAPID3 scores in patients with osteoarthritis or rheumatoid arthritis to assess disease burden associated with each rheumatic disease.
Tofacitinib may provide a fast and prolonged analgesic effect in patients with rheumatoid arthritis or psoriatic arthritis who are unresponsive to csDMARD or to TNFi, as well as in individuals with ankylosing spondylitis.
Based on these results, clinicians should consider assessing functional and mental health states before biologic tapering.
Researchers sought to determine whether a treat-to-target strategy based on MRI assessments targeting absence bone marrow edema would lead to improved clinical and radiographic outcomes.
Investigators sought to determine whether initial high disease activity or changes in disease activity contribute to the development of persistent depression among patients with early rheumatoid arthritis.
Results of the phase 3 SELECT-EARLY study show positive results for upadacitinib in adult patients with moderate to severe rheumatoid arthritis.
Mental health outcomes in patients with RA are unlikely to resolve with effective RA pharmacological disease management alone.
The FDA has approved baricitinib for the treatment of adults with active rheumatoid arthritis who have had an inadequate response to ≥1 tumor necrosis factor antagonist.
Researchers reported on the first outbreak of an Asian lineage of chikungunya virus in Aruba.
Children exposed to TNFi's during the gestational period were found not to have a significantly higher risk of developing serious infections.
Patients with rheumatoid arthritis with chronic hepatitis B virus infection demonstrated greater radiographic progression and poorer clinical response at 1 year.
In patients with rheumatoid arthritis or osteoarthritis who are at higher risk for cardiovascular events, celecoxib may be safer compared with naproxen or ibuprofen when these drugs are taken alone or in combination with aspirin.
Using a privately-insured administrative database, researchers examined a total of 78,704 patients with autoimmune or inflammatory disease diagnoses between 2006 and 2015.
This study sought to examine the link between early disease activity changes and attainment of LDA and remission targets in tofacitinib-treated patients with RA.
Rheumatology Advisor Articles
- Efficacy of ABT-122 Maintained in Psoriatic Arthritis, Rheumatoid Arthritis at 36 Weeks
- Comorbid Fibromyalgia Influences Disease Activity, Quality of Life in Axial Spondyloarthritis
- Knee Load Associated With Increased Walking Pain in Osteoarthritis
- Pain Catastrophizing Decreases in Rheumatoid Arthritis After DMARD Initiation
- CVD Prevention Measures Inadequate in Patients With Inflammatory Joint Diseases
- Genetic Screening May Predict Osteoporosis, Fracture Risk
- Exploring the Clinical Implications of Cannabinoid Use in Rheumatoid Arthritis
- Diagnosing Lyme Disease in Children With Neuropsychiatric Illness
- Predicting Primary Nonresponse to Methotrexate in Rheumatoid Arthritis
- Prednisone, Prednisolone Does Not Adversely Affect Bone Mineral Density in RA
- Sulfasalazine Reduces Pneumocystis Pneumonia Risk in Rheumatoid Arthritis
- DPP-4 Inhibitors and Incidence of Rheumatoid Arthritis in Type 2 Diabetes
- Response to Certolizumab Pegol at 12 Weeks Predicts Long-Term RA Outcomes
- Performance Phenotypes of Lumbar Spinal Stenosis and OA With Accelerometry Data
- Characteristics of Early-Onset SLE Distinguished From Mimicking Conditions