Rheumatoid Arthritis

Rheumatoid Arthritis and Diabetes: Reducing Cardiovascular Risk

Rheumatoid Arthritis and Diabetes: Reducing Cardiovascular Risk

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For patients with rheumatoid arthritis, abatacept conferred a greater reduction in CVD risk compared with TNF inihibitors.

Rheumatoid Arthritis Exposure In Utero Increases Chronic Disease Risk in Children

Rheumatoid Arthritis Exposure In Utero Increases Chronic Disease Risk in Children

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Maternal RA exposure in utero may increase the risk for certain chronic conditions, including RA, thyroid disease, and epilepsy.

Predicting Loss of Remission in RA Treated With Etanercept-Methotrexate

Predicting Loss of Remission in RA Treated With Etanercept-Methotrexate

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Investigators sought to determine which characteristics are predictive of remission induction and subsequent loss of remission in patients with moderately active RA.

Adalimumab Effective in JIA-Associated Uveitis Unresponsive to Methotrexate

Adalimumab Effective in JIA-Associated Uveitis Unresponsive to Methotrexate

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Adalimumab was well tolerated and associated with persistent uveitis improvement in most cases.

Comparing Tumor Necrosis Factor Inhibitors for RA and SpA: Overview & Expert Interview

Comparing Tumor Necrosis Factor Inhibitors for RA and SpA: Overview & Expert Interview

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They similarities and differences of anti-TNF drug function in RA and SpA are discussed in an expert interview.

Topical vs Oral NSAIDs for Rheumatoid Arthritis: Examining Cardiovascular Risks

Topical vs Oral NSAIDs for Rheumatoid Arthritis: Examining Cardiovascular Risks

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Researchers assessed the rates of composite cardiovascular events in people with RA using NSAIDs to treat musculoskeletal pain.

Prognostic Value of Thrombocytopenia in Valve Replacement Surgery for Rheumatic Heart Disease

Prognostic Value of Thrombocytopenia in Valve Replacement Surgery for Rheumatic Heart Disease

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Presence of thrombocytopenia at hospital admission may serve as an important prognostic marker for predicting in-hospital mortality for patients with RHD.

Risk for COPD, Asthma Examined in Women With Rheumatoid Arthritis

Risk for COPD, Asthma Examined in Women With Rheumatoid Arthritis

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RA-specific factors may predispose individuals to developing COPD independent of smoking.

New Studies Examine Potential Effects of Weight Loss, Obesity on Patient Health in RA

New Studies Examine Potential Effects of Weight Loss, Obesity on Patient Health in RA

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Findings from 2 studies examine the role that weight loss, obesity, and overweight play in disease activity, remission, and mortality in RA.

Leflunomide Exposure During Pregnancy Not Associated With Increased Risk for Adverse Outcomes

Leflunomide Exposure During Pregnancy Not Associated With Increased Risk for Adverse Outcomes

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The safety of leflunomide use for rheumatoid arthritis during pregnancy was examined in a prospective study.

Classical Disease-Modifying Antirheumatic Drugs: A Possible Treatment Option for Dementia?

Classical Disease-Modifying Antirheumatic Drugs: A Possible Treatment Option for Dementia?

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The protective effects of disease-modifying antirheumatic drugs in dementia was evaluated in a retrospective cohort study.

Choosing the Right TNF Inhibitor Therapy for Rheumatoid Arthritis

Choosing the Right TNF Inhibitor Therapy for Rheumatoid Arthritis

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There are important differences in TNFis for specific clinical conditions that recent research has made more apparent.

Improving Function Through Exercise in Rheumatoid Arthritis

Improving Function Through Exercise in Rheumatoid Arthritis

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Although recent pharmacologic advances have improved disease progression and prognosis in RA, a number of patients experience joint stiffness.

Clinical Outcomes With MTX Monotherapy vs TNFi-MTX Combination Therapy for Early RA

Clinical Outcomes With MTX Monotherapy vs TNFi-MTX Combination Therapy for Early RA

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A randomized study sough to evaluate whether methotrexate monotherapy can safely be started before treatment optimization with a tumor necrosis factor inhibitor in patients with early, active RA.

Characterization of Rheumatic Disorders Associated With Immune Checkpoint Inhibitor Use

Characterization of Rheumatic Disorders Associated With Immune Checkpoint Inhibitor Use

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A prospective, observational study sought to evaluate and characterize the nature of rheumatic disorders associated with immune checkpoint inhibitors.

Effect of bDMARD Discontinuation on Remission, Radiographic Progression in RA

Effect of bDMARD Discontinuation on Remission, Radiographic Progression in RA

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In patients with RA who have achieved remission or low disease activity (LDA), discontinuation of biologic disease-modifying antirheumatic drugs is associated with an increased risk for losing remission or LDA and radiographic progression.

Pneumonia Incidence in Rheumatic Disease Lowered With Primary Prophylaxis

Pneumonia Incidence in Rheumatic Disease Lowered With Primary Prophylaxis

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In patients with rheumatic diseases, the incidence of pneumocystis pneumonia was reduced with primary prophylaxis with trimethoprim/sulfamethoxazole.

Pregnancy in Inflammatory Arthritis: What Your Patients Need to Know

Pregnancy in Inflammatory Arthritis: What Your Patients Need to Know

Megan Clowse, MD, MPH, discusses 2 studies that examine reproductive health concerns in women with inflammatory rheumatic diseases.

Tocilizumab Reduces Bone Loss in ACPA-Positive Rheumatoid Arthritis

Tocilizumab Reduces Bone Loss in ACPA-Positive Rheumatoid Arthritis

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Tocilizumab treatment for 2 years was shown to reduce levels of bone loss in patients with ACPA-positive RA.

Early Treatment of Undifferentiated Arthritis May Delay Subsequent RA Progression

Early Treatment of Undifferentiated Arthritis May Delay Subsequent RA Progression

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Early treatment of undifferentiated arthritis may delay progression to rheumatoid arthritis.

Biologics Not Linked to Increased Risk of Second Malignancy in RA

Biologics Not Linked to Increased Risk of Second Malignancy in RA

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Using biologics to treat rheumatoid arthritis patients does not appear to increase the risk of a second malignancy in individuals with history of cancer.

Serious Infections Uncommon in Patients With RA Treated With bDMARD With or Without Denosumab

Serious Infections Uncommon in Patients With RA Treated With bDMARD With or Without Denosumab

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In patients with rheumatoid arthritis being treated with a biologic disease-modifying antirheumatic drug with and without denosumab, serious and opportunistic infections are uncommon.

Assessing Fear, Psychological Distress in Rheumatoid Arthritis and Axial Spondyloarthritis

Assessing Fear, Psychological Distress in Rheumatoid Arthritis and Axial Spondyloarthritis

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The Fear Assessment in Inflammatory Rheumatic diseases questionnaire may be useful to evaluate the levels of fear and psychological distress in patients with rheumatoid arthritis and axial spondyloarthritis.

Risk for Prosthetic Joint Infection, Surgical Revision After Total Joint Arthroplasty in RA

Risk for Prosthetic Joint Infection, Surgical Revision After Total Joint Arthroplasty in RA

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Patients with rheumatoid arthritis may be at increased risk for prosthetic joint infection and death after total knee or hip arthroplasty, compared with patients with osteoarthritis.

Increased Risk for COPD in Rheumatoid Arthritis

Increased Risk for COPD in Rheumatoid Arthritis

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Patients with rheumatoid arthritis appear to be at increased risk for chronic obstructive pulmonary disease.

Topical vs Oral NSAIDs and the Risk for Cardiovascular Events in RA

Topical vs Oral NSAIDs and the Risk for Cardiovascular Events in RA

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Topical NSAIDs are associated with a lower risk for cardiovascular events compared with oral NSAIDs in patients with rheumatoid arthritis.

Risk for COPD, Asthma Among Women With Rheumatoid Arthritis: Nurses' Health Study

Risk for COPD, Asthma Among Women With Rheumatoid Arthritis: Nurses' Health Study

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The Nurses' Health Study was used to assess the risk of COPD and asthma in women with rheumatoid arthritis.

Discontinuation of Biosimilar Infliximab Associated With Subjective Complaints

Discontinuation of Biosimilar Infliximab Associated With Subjective Complaints

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Transitioning from an originator agent to its biosimilar has the potential to reduce healthcare costs without compromising outcomes.

Rheumatologic Disorders Increase Risk for Guillain-Barré Syndrome

Rheumatologic Disorders Increase Risk for Guillain-Barré Syndrome

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A future risk for Guillain-Barré syndrome is correlated with early life immune disorders.

Endothelial Function Improves With Methotrexate, Anti-TNF Therapy in Inflammatory Arthritis

Endothelial Function Improves With Methotrexate, Anti-TNF Therapy in Inflammatory Arthritis

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Although the effect of antirheumatic drugs on inflammatory arthritic conditions has not been fully elucidated, treatment with methotrexate and tumor necrosis factor inhibitors has been found to improve endothelial dysfunction in this population.

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