Case Study and Clinical Highlight: Diagnosis of Pulmonary Involvement in Systemic Sclerosis

Case Study and Clinical Highlight: Diagnosis of Pulmonary Involvement in Systemic Sclerosis

Engage in this case study to test your diagnostic ability to differentiate pulmonary hypertension in the setting of systemic sclerosis.

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Reduced Right Ventricular Output Reserve Observed in SSc With Elevated PAP

Reduced Right Ventricular Output Reserve Observed in SSc With Elevated PAP

Investigators examined right ventricular function and pulmonary arterial compliance at rest and during exercise in patients with systemic sclerosis with normal or mildly elevated mean pulmonary artery pressures, or with manifest pulmonary hypertension.

Assessing Retinal Microvascular Perfusion in Systemic Sclerosis

Assessing Retinal Microvascular Perfusion in Systemic Sclerosis

Researchers used optical coherence tomography angiography to measure retinal microvascular blood flow in patients with systemic sclerosis with no clinical signs of retinal involvement.

Biomarkers Predictive of Systemic Sclerosis-Interstitial Lung Disease Identified

Biomarkers Predictive of Systemic Sclerosis-Interstitial Lung Disease Identified

Lung‐epithelial‐derived surfactant protein has been identified as a biomarker of systemic sclerosis-interstitial lung disease.

Novel Blood Test May Aid Scleroderma Diagnosis and Risk Stratification

Novel Blood Test May Aid Scleroderma Diagnosis and Risk Stratification

Mark Pimentel, MD, discusses the release of a new blood test that may aid in the diagnosis of scleroderma and systemic sclerosis.

Systemic Sclerosis-Associated PAH Genomic Signature Differs From ILD

Systemic Sclerosis-Associated PAH Genomic Signature Differs From ILD

Systemic sclerosis-associated pulmonary hypertension and systemic sclerosis-associated interstitial lung disease exhibit similar but distinct gene expression profiles.

Ulnar Artery Occlusion: A Vasculopathy Severity Marker in SSc

Ulnar Artery Occlusion: A Vasculopathy Severity Marker in SSc

Ulnar artery occlusion may function as a relevant marker of vasculopathy severity in systematic sclerosis.

Severe Gastrointestinal Disease in Early Systemic Sclerosis Linked to Increased Morbidity, Mortality

Severe Gastrointestinal Disease in Early Systemic Sclerosis Linked to Increased Morbidity, Mortality

Severe gastrointestinal disease is common in early systemic sclerosis, and is linked to increased mortality.

Increased Prevalence of Systemic Sclerosis Observed in the United Kingdom

Increased Prevalence of Systemic Sclerosis Observed in the United Kingdom

Researchers estimated the incidence and prevalence of systemic sclerosis in recent years in the United Kingdom.

Exercise Oxygen Desaturation, Pulmonary Function Predict Outcomes in SSc-PH

Exercise Oxygen Desaturation, Pulmonary Function Predict Outcomes in SSc-PH

Factors associated with a higher risk for mortality included male sex, exercise desaturation, and diffusing capacity of the lungs for carbon monoxide <50%.

Short-Term Progression of Interstitial Lung Disease in Systemic Sclerosis Predictive of Long-Term Survival

Short-Term Progression of Interstitial Lung Disease in Systemic Sclerosis Predictive of Long-Term Survival

A decline in FVC and DLCO over 2 years was a better predictor of mortality than baseline FVC and DLCO.

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