Case Study and Clinical Highlight: Diagnosis of Pulmonary Involvement in Systemic Sclerosis

Case Study and Clinical Highlight: Diagnosis of Pulmonary Involvement in Systemic Sclerosis

Engage in this case study to test your diagnostic ability to differentiate pulmonary hypertension in the setting of systemic sclerosis.

Latest News

Increased Prevalence of Systemic Sclerosis Observed in the United Kingdom

Increased Prevalence of Systemic Sclerosis Observed in the United Kingdom

Researchers estimated the incidence and prevalence of systemic sclerosis in recent years in the United Kingdom.

Exercise Oxygen Desaturation, Pulmonary Function Predict Outcomes in SSc-PH

Exercise Oxygen Desaturation, Pulmonary Function Predict Outcomes in SSc-PH

Factors associated with a higher risk for mortality included male sex, exercise desaturation, and diffusing capacity of the lungs for carbon monoxide <50%.

Short-Term Progression of Interstitial Lung Disease in Systemic Sclerosis Predictive of Long-Term Survival

Short-Term Progression of Interstitial Lung Disease in Systemic Sclerosis Predictive of Long-Term Survival

A decline in FVC and DLCO over 2 years was a better predictor of mortality than baseline FVC and DLCO.

High-Resolution CT Useful in Systemic Sclerosis-Associated ILD Screening

High-Resolution CT Useful in Systemic Sclerosis-Associated ILD Screening

Clinicians should incorporate chest high-resolution computed tomography when screening patients with systemic sclerosis-associated interstitial lung disease even when pulmonary function tests results are normal.

On-Demand Sildenafil May Be Promising Second-Line Treatment for Raynaud Phenomenon

On-Demand Sildenafil May Be Promising Second-Line Treatment for Raynaud Phenomenon

Results did not show that on-demand sildenafil was more effective than placebo from a clinical standpoint.

Depression Prevalent Among Individuals With Systemic Sclerosis

Depression Prevalent Among Individuals With Systemic Sclerosis

Depression is prevalent in a considerable proportion of patients with systemic sclerosis.

Statin Initiation Reduces Overall Mortality in Systemic Autoimmune Rheumatic Diseases

Statin Initiation Reduces Overall Mortality in Systemic Autoimmune Rheumatic Diseases

The initiation of statin therapy is associated with reduced overall mortality in patients with systemic autoimmune rheumatic diseases.

Ultrasonographic Synovial Involvement Frequent in Systemic Sclerosis

Ultrasonographic Synovial Involvement Frequent in Systemic Sclerosis

Ultrasonographic synovial involvement is frequent in patients with systemic sclerosis.

Gene Therapy for Localized Scleroderma Gets FDA's Fast Track Designation

Gene Therapy for Localized Scleroderma Gets FDA's Fast Track Designation

Clinical enrollment for an open-label, single-arm Phase 1/2 trial of FCX-013 was initiated in August 2018.

Rituximab Safe and Efficacious Alternative Treatment for Scleroderma

Rituximab Safe and Efficacious Alternative Treatment for Scleroderma

Rituximab is a safe and effective alternative to cyclophosphamide in managing the progression of scleroderma and subsequent development of interstitial lung disease.

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