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Spondyloarthritis Immunogenicity of Golimumab Validated Using Novel Anti-Drug Antibody Detection Assay

Immunogenicity of Golimumab Validated Using Novel Anti-Drug Antibody Detection Assay

Antidrug antibody incidence was higher using drug-tolerant vs original enzyme immunoassays in patients treated with golimumab.

Spondyloarthritis CRP Levels May Predict Treatment Response in Ankylosing Spondylitis

CRP Levels May Predict Treatment Response in Ankylosing Spondylitis

C-reactive protein levels may be an effective predictive measure to assess treatment response in patients with ankylosing spondylitis.

Spondyloarthritis Filgotinib Safe, Effective for Treatment of Active Ankylosing Spondylitis

Filgotinib Safe, Effective for Treatment of Active Ankylosing Spondylitis

The TORTUGA trial investigated the efficacy and safety of filgotinib for the treatment of patients with active ankylosing spondylitis.

Spondyloarthritis Low Incidence of Vertebral Fractures Observed in Early Spondyloarthritis

Low Incidence of Vertebral Fractures Observed in Early Spondyloarthritis

The incidence of vertebral fracture in SpA was lower than that reported in previous studies.

Spondyloarthritis Red Cell Distribution Width Linked to Cardiovascular Disease Risk Factors in Spondyloarthritis

Red Cell Distribution Width Linked to Cardiovascular Disease Risk Factors in Spondyloarthritis

CVD risk factors were associated with red blood cell distribution and albumin and red blood cell distribution was also associated with age, albumin, hemoglobin, race, HLAB27 status, CRP, and statin treatment.

Spondyloarthritis Workplace, Clinical Factors Linked to Employment Outcomes in Axial Spondyloarthritis

Workplace, Clinical Factors Linked to Employment Outcomes in Axial Spondyloarthritis

Data identified both clinical and employment factors that may predict poor work outcomes in patients with axial spondyloarthritis.

Spondyloarthritis Spinal Radiographic Progression May Be Observed Early in Disease Course for axSpA

Spinal Radiographic Progression May Be Observed Early in Disease Course for axSpA

Higher radiographic progression was associated with increased inflammation and damage in early axial spondyloarthritis.

Spondyloarthritis Gender-Specific Approaches Not Warranted for Early Axial Spondyloarthritis Diagnosis

Gender-Specific Approaches Not Warranted for Early Axial Spondyloarthritis Diagnosis

Results do not suggest that separate diagnostic strategies for men and women are required.

Spondyloarthritis TNFi Therapy Did Not Prevent Joint Ankylosis in Young Patients With Spondyloarthritis

TNFi Therapy Did Not Prevent Joint Ankylosis in Young Patients With Spondyloarthritis

TNFi therapy failed to prevent the development of joint ankylosis despite a substantial reduction in inflammation with TNFi therapy.

Spondyloarthritis Ixekizumab Tops Placebo in Axial Spondyloarthritis

Ixekizumab Tops Placebo in Axial Spondyloarthritis

For patients with active radiographic axSpA and prior inadequate response or intolerance to 1 or 2 TNFi, ixekizumab treatment results in significant improvements vs placebo.

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