In patients with psoriatic arthritis, increasing levels of HLA-B27 are associated with more severe sonographic enthesitis.
Results of the GESPIC study found that structural damage in the spine and disease activity were both determinants of functional status and spine mobility in patients with early axial spondyloarthritis.
Decreases in spinal and sacroiliac joint inflammation on MRI were maintained through 204 weeks with certolizumab pegol treatment.
The risk for aortic regurgitation and cardiac rhythm abnormalities was evaluated in a nationwide cohort of patients with spondyloarthritis.
Results from the phase 3 SPIRIT-P1 study show that treatment with ixekizumab every 2 or 4 weeks in patients with active psoriatic arthritis demonstrated sustained efficacy and a favorable safety profile.
Patients with psoriatic arthritis who are taking apremilast experienced early symptom relief and sustained clinical improvement through 1 year of treatment.
Spinal fracture-free survival among patients with AS was not significantly affected by the use of bDMARD therapy.
In an update to recommendations from 2012, an international task force conducted a systematic evidence review of data from the last 5 years.
Research suggests that the best site to assess bone loss in patients with ankylosing spondylitis is the femoral neck.
The diagnostic utility of repeat MRI was examined in people who were HLA-B27-negative or positive.
Smoking is positively associated with the risk for PsA in the general population, but negatively associated with PsA in patients with psoriasis.
The Psoriatic Arthritis Impact of Disease Questionnaire is a reliable patient-reported outcome measure with utility among patients with psoriatic arthritis in clinical practice.
Transitioning from an originator agent to its biosimilar has the potential to reduce healthcare costs without compromising outcomes.
The use of tumor necrosis factor inhibitors to modify structural changes in axial spondyloarthritis may prevent progression to spinal disease.
Although the effect of antirheumatic drugs on inflammatory arthritic conditions has not been fully elucidated, treatment with methotrexate and tumor necrosis factor inhibitors has been found to improve endothelial dysfunction in this population.
Researchers sought to learn more about the "background noise" of MRI features in the sacroiliac joints of young athletes.
For patients with ankylosing spondylitis, secukinumab may reduce radiographic progression and remain effective in the long-term.
The risk for cerebrovascular accidents and myocardial infarctions was assessed in patients with ankylosing spondylitis.
MRI examination of structural lesions of the sacroiliac joints and the spine may help identify and classify axial spondyloarthritis.
Inflammation shown on MRI of the sacroiliac joint (MRI-SI) is prevalent in axSpA (±30%), but the specificity is not well known.
Administration of abatacept may improve patient-reported outcomes in individuals with active psoriatic arthritis and elevated levels of C-reactive protein, irrespective of tumor necrosis factor inhibitor treatment history.
The guideline includes recommendations for treating adult patients with active psoriatic arthritis.
Regardless of dose, patients taking secukinumab were more likely to experience no radiographic progression compared with placebo.
Treatment with TNF inhibitors has led to improvement in physical function and quality of life in patients with ankylosing spondylitis.
Results from phase 3 trials OPAL Broaden (NCT01877668) and OPAL Beyond (NCT01882439) presented at the American College of Rheumatology 2017 in San Diego, California.
Researchers recruited patients with recent onset axial spondyloarthritis and conducted MRI of the spine or MRI of the sacroiliac joints at baseline, 2 years, and 5 years.
With the exception of sedentary lifestyle, cardiovascular risk factors were not found to impact the likelihood of achieving minimal disease activity among patients with psoriatic arthritis.
Researchers observed a higher prevalence of psychiatric disorders among female patients with psoriatic arthritis.
Recognition of the negative consequences of being obese is vital to effectively managing axial spondyloarthropathy.
Real-world data indicate that although most patients with systemic lupus erythematosus or connective tissue diseases have successful pregnancies, more adverse pregnancy outcomes occur.
Rheumatology Advisor Articles
- Raynaud Phenomenon, Migraine Linked to aPS/PT Antibodies in Primary Antiphospholipid Syndrome
- Then and Now: The Crisis of Physician Suicides
- Case Study: A Syncopal Episode During a Camping Trip
- Salivary Gland Ultrasound Scores Improved With Rituximab in Primary Sjogren's Syndrome
- Joint Replacement Rates in OA With Diabetes: Effects of COX-2 Inhibitors Plus Metformin
- FDA Advises Recall: Limbrel May Be Linked to Drug-Induced Liver Injury
- Allopurinol Use May Lower Risk for Peripheral Arterial Disease
- Managing Treatment Nonadherence in Rheumatic Diseases
- Optimal Fibromyalgia Management Includes Individualized, Multimodal Therapy
- Risk for COPD, Asthma Among Women With Rheumatoid Arthritis: Nurses' Health Study
- Aspirin Effective for VTE Prophylaxis After Hip, Knee Arthroplasty
- Short-Form Patient-Reported Outcomes Tool Effective in SLE
- Burnout Prevalence High Among Physicians in Single Health System
- Expert Insight: Discussing Sensitive Topics With Patients
- Increased HLA-B27 Associated With More Severe Sonographic Enthesitis in PsA