Spondyloarthritis

Identifying Early Structural Changes in Axial Spondyloarthritis: A Comparison of Scoring Methods

Identifying Early Structural Changes in Axial Spondyloarthritis: A Comparison of Scoring Methods

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Investigators compared the performance of different spinal radiographic damage scoring methods in patients with early axial spondyloarthritis.

Efficacy of ABT-122 Maintained in Psoriatic Arthritis, Rheumatoid Arthritis at 36 Weeks

Efficacy of ABT-122 Maintained in Psoriatic Arthritis, Rheumatoid Arthritis at 36 Weeks

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ABT-122 demonstrated acceptable tolerability and maintenance of efficacy at 36 weeks in patients with RA or PsA receiving background methotrexate.

Comorbid Fibromyalgia Influences Disease Activity, Quality of Life in Axial Spondyloarthritis

Comorbid Fibromyalgia Influences Disease Activity, Quality of Life in Axial Spondyloarthritis

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Meeting the criteria for fibromyalgia had a modest effect on disease activity and did not influence the response to TNFi therapy.

Minimal Disease Activity Provides Valid Assessment of Adalimumab-Treated Psoriatic Arthritis

Minimal Disease Activity Provides Valid Assessment of Adalimumab-Treated Psoriatic Arthritis

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Minimal disease activity provided a stable and valid assessment of clinical status over the course of 24 months in patients with psoriatic arthritis.

Few Sonographic Enthesitis Scoring Instruments Validated in Psoriatic Arthritis

Few Sonographic Enthesitis Scoring Instruments Validated in Psoriatic Arthritis

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Sonographic enthesitis scoring instruments have been developed for spondyloarthritis, but only a few have been validated in psoriatic arthritis.

Depression Associated With More Severe Disease Activity, Functional Impairment in axSpA

Depression Associated With More Severe Disease Activity, Functional Impairment in axSpA

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Depression is common in patients with axSpA and is associated with more severe disease activity and functional impairment.

Prevalence of Psoriatic Arthritis Quantified in Patients With Psoriasis

Prevalence of Psoriatic Arthritis Quantified in Patients With Psoriasis

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Researchers sought to estimate the occurrence of psoriatic arthritis in patients with psoriasis.

TNFi Effectively Decreases Radiographic Progression in Early Ankylosing Spondylitis

TNFi Effectively Decreases Radiographic Progression in Early Ankylosing Spondylitis

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Effective suppression of inflammation with tumor necrosis factor inhibitor therapy decreases radiographic progression in early ankylosing spondylitis.

Rates of Knee, Hip Arthroplasty Increasing Among Patients With Ankylosing Spondylitis

Rates of Knee, Hip Arthroplasty Increasing Among Patients With Ankylosing Spondylitis

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Researchers observed increased rates of both knee and hip arthroplasties in older patients with ankylosing spondylitis.

Widespread Pain Common, Linked to Worse Patient-Reported Disease Activity in PsA

Widespread Pain Common, Linked to Worse Patient-Reported Disease Activity in PsA

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Widespread nonarthritic pain is linked to worse patient-reported and composite psoriatic arthritis activity measures.

Axial Involvement in Psoriatic Arthritis Associated With Poorer Clinical Outcomes, Quality of Life

Axial Involvement in Psoriatic Arthritis Associated With Poorer Clinical Outcomes, Quality of Life

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Researchers analyzed the characteristics of patients with psoriatic arthritis with and without axial involvement.

Examining the Influence of Disease Manifestations on Quality of Life in Psoriatic Arthritis

Examining the Influence of Disease Manifestations on Quality of Life in Psoriatic Arthritis

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Health-related quality of life was diminished in psoriatic arthritis at time of diagnosis compared with the general population.

Lower Cardiorespiratory Fitness Associated With Increased CVD Risk in Ankylosing Spondylitis

Lower Cardiorespiratory Fitness Associated With Increased CVD Risk in Ankylosing Spondylitis

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Reduced cardiorespiratory fitness may be associated with increased risk for CVD in ankylosing spondylitis.

Differentiating Between axSpA, Degenerative Disease Abnormalities on MRI, Radiographs

Differentiating Between axSpA, Degenerative Disease Abnormalities on MRI, Radiographs

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Researchers sought to assess whether it is possible to discriminate between degenerative changes and lesions associated with axSpA.

Risankizumab May Not Be Effective in Treatment of Ankylosing Spondylitis

Risankizumab May Not Be Effective in Treatment of Ankylosing Spondylitis

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Treatment with risankizumab was not effective in reducing the signs and symptoms of ankylosing spondylitis at 12 weeks.

Adalimumab Continuation Linked to Fewer Flares After Remission in Nonradiographic axSpA

Adalimumab Continuation Linked to Fewer Flares After Remission in Nonradiographic axSpA

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In patients with nonradiographic axial spondyloarthritis who achieve remission with adalimumab, continued therapy was linked to fewer flares vs treatment withdrawal.

Physician's Global Assessment Reliable for Evaluating Disease Activity in Psoriatic Arthritis

Physician's Global Assessment Reliable for Evaluating Disease Activity in Psoriatic Arthritis

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Researchers sought to assess the reliability of the PGA for musculoskeletal and dermatologic manifestations in patients with psoriatic arthritis.

High-Intensity Interval Training Has No Effect on Disease Activity in Psoriatic Arthritis

High-Intensity Interval Training Has No Effect on Disease Activity in Psoriatic Arthritis

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High-intensity interval training showed no clear effects on disease activity markers in patients with psoriatic arthritis.

Similar Quality of Life Reported in Rheumatoid Arthritis, Psoriatic Arthritis

Similar Quality of Life Reported in Rheumatoid Arthritis, Psoriatic Arthritis

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Health-related quality of life was similar in patients with rheumatoid arthritis and psoriatic arthritis.

Novel Automated Mobility Measure Yields High Reproducibility in Axial Spondyloarthritis

Novel Automated Mobility Measure Yields High Reproducibility in Axial Spondyloarthritis

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Researchers assessed the reproducibility of UCOASMI in clinical practice settings.

TNFi More Effective in Men vs Women With Psoriatic Arthritis

TNFi More Effective in Men vs Women With Psoriatic Arthritis

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Male gender was associated with better biologic treatment effectiveness in psoriatic arthritis.

Positive Phase 3 Data Announced for Ixekizumab in Ankylosing Spondylitis

Positive Phase 3 Data Announced for Ixekizumab in Ankylosing Spondylitis

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Results from a phase 3 study show positive results for ixekizumab in patients with ankylosing spondylitis.

Gender Differences in Axial Spondyloarthritis: Comparing Disease Burden and Treatment

Gender Differences in Axial Spondyloarthritis: Comparing Disease Burden and Treatment

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An improved understanding of the gender differences in axial spondyloarthritis can improve disease treatment and reduce disease burden.

ASAS Health Index Valid, Reliable in Axial and Peripheral Spondyloarthritis

ASAS Health Index Valid, Reliable in Axial and Peripheral Spondyloarthritis

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The Assessment of Spondyloarthritis International Society Health Index proved to be valid, reliable, and responsive.

Ankylosing Spondylitis Linked to Increased Prevalence of Left Ventricular Hypertrophy

Ankylosing Spondylitis Linked to Increased Prevalence of Left Ventricular Hypertrophy

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Data strengthen the indication for performing a thorough CVD risk assessment in patients with inflammatory disorders.

Fatigue Affects Work Disability in Rheumatoid Arthritis, Ankylosing Spondylitis

Fatigue Affects Work Disability in Rheumatoid Arthritis, Ankylosing Spondylitis

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Fatigue had a significant and independent effect on work disability measures in rheumatoid arthritis and ankylosing spondylitis.

ABT-122 Shows Similar Safety, Efficacy to Adalimumab in Psoriatic Arthritis

ABT-122 Shows Similar Safety, Efficacy to Adalimumab in Psoriatic Arthritis

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ABT-122 demonstrated efficacy and safety similar to adalimumab over 12 weeks in patients with psoriatic arthritis who had an inadequate response to methotrexate.

FDA: Secukinumab Slows Progression of Joint Structural Damage in Psoriatic Arthritis

FDA: Secukinumab Slows Progression of Joint Structural Damage in Psoriatic Arthritis

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The FDA has approved updated labeling for Cosentyx that includes data demonstrating that the drug slows the progression of joint structural damage in patients with active psoriatic arthritis.

Axial Psoriatic Arthritis and Ankylosing Spondylitis: Comparing Clinical, Radiologic Characteristics

Axial Psoriatic Arthritis and Ankylosing Spondylitis: Comparing Clinical, Radiologic Characteristics

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It is unclear whether ankylosing spondylitis and axial psoriatic arthritis are part of a spectrum of the same disease, or whether they are separate diseases with overlapping features.

Early, Sustained Improvements With Apremilast in Biologic-Naive Psoriatic Arthritis

Early, Sustained Improvements With Apremilast in Biologic-Naive Psoriatic Arthritis

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In biologic-naive patients with psoriatic arthritis who are treated with apremilast, early onset of effect was observed across disease PsA manifestations.

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