Spondyloarthritis

Utility of Repeated C-Reactive Protein Testing Nonradiographic Axial Spondyloarthritis

Utility of Repeated C-Reactive Protein Testing Nonradiographic Axial Spondyloarthritis

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Results suggest that C-reactive protein testing should be repeated after at least 4 weeks.

Risk for Type 2 Diabetes, Cardiovascular Disease Elevated in Patients With Psoriatic Arthritis

Risk for Type 2 Diabetes, Cardiovascular Disease Elevated in Patients With Psoriatic Arthritis

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Risk for type 2 diabetes, ischemic heart disease, and peripheral vascular disease was elevated among patients with psoriatic arthritis compared with the general population.

MRI Indicates Sacroiliitis in Some Healthy Individuals

MRI Indicates Sacroiliitis in Some Healthy Individuals

Magnetic resonance imaging positive for sacroiliitis is seen in a considerable number of healthy individuals without back pain.

Sustained Improvements in PsA With Certolizumab Pegol Monotherapy, DMARD Combination

Sustained Improvements in PsA With Certolizumab Pegol Monotherapy, DMARD Combination

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Results from the RAPID-PsA study showed that patients with PsA who are treated with certolizumab pegol sustained improvements over the course of 4 years when it is taken as a monotherapy or concomitant with DMARDs.

Incidence, Predictors of Orthopedic Surgery in Psoriatic Arthritis

Incidence, Predictors of Orthopedic Surgery in Psoriatic Arthritis

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Researchers quantified the incidence of orthopedic procedures in patients with psoriatic arthritis.

Effects of Age, Disease Duration on Bone Erosions in Psoriasis, Psoriatic Arthritis

Effects of Age, Disease Duration on Bone Erosions in Psoriasis, Psoriatic Arthritis

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Data show that psoriatic arthritis acts as a strong enhancer of age-related catabolic bone damage.

Assessing Disease Activity During, After Pregnancy in Psoriatic Arthritis

Assessing Disease Activity During, After Pregnancy in Psoriatic Arthritis

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Disease activity was altogether low and stable from preconception to 1 year postpartum among pregnant women with psoriatic arthritis.

Juvenile Spondyloarthritis Disease Activity Index Valid in Children With Enthesitis-Related Arthritis

Juvenile Spondyloarthritis Disease Activity Index Valid in Children With Enthesitis-Related Arthritis

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The Juvenile Spondyloarthritis Disease Activity Index is an appropriate measure of disease activity for enthesitis-related arthritis.

Ixekizumab Demonstrates No New Safety Concerns for Treatment of Psoriatic Arthritis

Ixekizumab Demonstrates No New Safety Concerns for Treatment of Psoriatic Arthritis

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The safety profile of ixekizumab in the treatment of psoriatic arthritis is similar to the safety profile observed with ixekizumab for the treatment of plaque psoriasis.

Hospitalized Infection Risk Not Linked to DMARD, TNFi Use in Ankylosing Spondylitis

Hospitalized Infection Risk Not Linked to DMARD, TNFi Use in Ankylosing Spondylitis

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No clear evidence links the risk for hospitalized infection and the use of DMARDs or anti-TNF agents in patients with ankylosing spondylitis.

Greater Baseline Symptom Burden Linked to Poorer TNFi Response Rates in axSpA

Greater Baseline Symptom Burden Linked to Poorer TNFi Response Rates in axSpA

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Patients who reported a greater symptom burden at the start of TNFi treatment had poor response rates and low retention rates.

Juvenile Spondyloarthritis: Classification and Treatment Considerations

Juvenile Spondyloarthritis: Classification and Treatment Considerations

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Juvenile spondyloarthritis is a distinct form of childhood arthritis because of the male predominance, later age of onset, and involvement of the entheses and axial skeleton.

OMERACT Group Develops Reliable Ultrasound Definition of Enthesitis in PsA, SpA

OMERACT Group Develops Reliable Ultrasound Definition of Enthesitis in PsA, SpA

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A final reliable ultrasound score and definition of enthesitis in SpA and PsA were produced by the OMERACT group.

MR-VIBE More Sensitive for Detecting Erosions in Sacroiliac Joints

MR-VIBE More Sensitive for Detecting Erosions in Sacroiliac Joints

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VIBE detected erosions in the sacroiliac joints with higher sensitivity without a loss of specificity and superior reliability compared with a standard T1-weighted sequence.

Gender Differences, Clinical Outcomes of Pain in Axial Spondyloarthritis

Gender Differences, Clinical Outcomes of Pain in Axial Spondyloarthritis

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The location and spread of pain in patients with axial spondyloarthritis was different between genders and was related to worse clinical status.

Biologic Therapy Improves Work Productivity in Axial Spondyloarthritis

Biologic Therapy Improves Work Productivity in Axial Spondyloarthritis

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Consistent data show that treatment with biologic therapy significantly improves work productivity and activity impairment among patients with axial spondyloarthritis.

Assessment of Simultaneous Occurrence of Ankylosing Spondylitis and Diffuse Idiopathic Skeletal Hyperostosis

Assessment of Simultaneous Occurrence of Ankylosing Spondylitis and Diffuse Idiopathic Skeletal Hyperostosis

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Researchers explored the co-occurrence of ankylosing spondylitis and diffuse idiopathic skeletal hyperostosis.

Reduced Synovial Inflammation With Secukinumab in Psoriatic Arthritis

Reduced Synovial Inflammation With Secukinumab in Psoriatic Arthritis

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Treatment with secukinumab over 24 weeks led to a decrease of synovial inflammation and no progression of catabolic and anabolic bone changes in patients with PsA.

Extended Efficacy of Ixekizumab in Psoriatic Arthritis With Prior Inadequate TNFi Response

Extended Efficacy of Ixekizumab in Psoriatic Arthritis With Prior Inadequate TNFi Response

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The overall safety profile of ixekizumab in psoriatic arthritis remained consistent with that reported in the initial 24-week, double-blind study period.

Identifying Early Structural Changes in Axial Spondyloarthritis: A Comparison of Scoring Methods

Identifying Early Structural Changes in Axial Spondyloarthritis: A Comparison of Scoring Methods

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Investigators compared the performance of different spinal radiographic damage scoring methods in patients with early axial spondyloarthritis.

Efficacy of ABT-122 Maintained in Psoriatic Arthritis, Rheumatoid Arthritis at 36 Weeks

Efficacy of ABT-122 Maintained in Psoriatic Arthritis, Rheumatoid Arthritis at 36 Weeks

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ABT-122 demonstrated acceptable tolerability and maintenance of efficacy at 36 weeks in patients with RA or PsA receiving background methotrexate.

Comorbid Fibromyalgia Influences Disease Activity, Quality of Life in Axial Spondyloarthritis

Comorbid Fibromyalgia Influences Disease Activity, Quality of Life in Axial Spondyloarthritis

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Meeting the criteria for fibromyalgia had a modest effect on disease activity and did not influence the response to TNFi therapy.

Minimal Disease Activity Provides Valid Assessment of Adalimumab-Treated Psoriatic Arthritis

Minimal Disease Activity Provides Valid Assessment of Adalimumab-Treated Psoriatic Arthritis

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Minimal disease activity provided a stable and valid assessment of clinical status over the course of 24 months in patients with psoriatic arthritis.

Few Sonographic Enthesitis Scoring Instruments Validated in Psoriatic Arthritis

Few Sonographic Enthesitis Scoring Instruments Validated in Psoriatic Arthritis

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Sonographic enthesitis scoring instruments have been developed for spondyloarthritis, but only a few have been validated in psoriatic arthritis.

Depression Associated With More Severe Disease Activity, Functional Impairment in axSpA

Depression Associated With More Severe Disease Activity, Functional Impairment in axSpA

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Depression is common in patients with axSpA and is associated with more severe disease activity and functional impairment.

Prevalence of Psoriatic Arthritis Quantified in Patients With Psoriasis

Prevalence of Psoriatic Arthritis Quantified in Patients With Psoriasis

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Researchers sought to estimate the occurrence of psoriatic arthritis in patients with psoriasis.

TNFi Effectively Decreases Radiographic Progression in Early Ankylosing Spondylitis

TNFi Effectively Decreases Radiographic Progression in Early Ankylosing Spondylitis

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Effective suppression of inflammation with tumor necrosis factor inhibitor therapy decreases radiographic progression in early ankylosing spondylitis.

Rates of Knee, Hip Arthroplasty Increasing Among Patients With Ankylosing Spondylitis

Rates of Knee, Hip Arthroplasty Increasing Among Patients With Ankylosing Spondylitis

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Researchers observed increased rates of both knee and hip arthroplasties in older patients with ankylosing spondylitis.

Widespread Pain Common, Linked to Worse Patient-Reported Disease Activity in PsA

Widespread Pain Common, Linked to Worse Patient-Reported Disease Activity in PsA

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Widespread nonarthritic pain is linked to worse patient-reported and composite psoriatic arthritis activity measures.

Axial Involvement in Psoriatic Arthritis Associated With Poorer Clinical Outcomes, Quality of Life

Axial Involvement in Psoriatic Arthritis Associated With Poorer Clinical Outcomes, Quality of Life

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Researchers analyzed the characteristics of patients with psoriatic arthritis with and without axial involvement.

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