Data support the clinical efficacy of low-dose leflunomide combined with prednisone for the treatment of proliferative lupus nephritis.
Intrauterine fetal death may be an early sign of antiphospholipid syndrome in pregnant women.
Risk factors for psychosis in SLE included male sex and African ancestry.
Researchers examined the role of CB-CAPs for diagnosis and monitoring of pediatric-onset SLE.
Investigators evaluated the immunogenicity of pneumococcal vaccination in children with systemic lupus erythematosus.
A positive direct Coombs test in the absence of hemolytic anemia may be a useful biomarker for assessing disease activity in systemic lupus erythematosus.
High and low HCQ levels were associated with preterm birth and disease activity in SLE.
Long-term treatment of SLE with belimumab with standard of care resulted in sustained benefits in patient fatigue and health-related quality of life.
A strong association between antiphospholipid positivity and first-time MI may represent a risk factor for myocardial infarction.
Investigators sought to define the clinical association of clinical and imaging definitions of synovitis in patients with SLE with musculoskeletal symptoms.
Researchers identified SERPINA3 as a potential urine biomarker to quantify lupus nephritis.
Researchers sought to determine whether a cardiovascular magnetic resonance protocol may be useful for early diagnosis of heart disease in patients with systemic lupus erythematosus.
Results from a phase 2 study suggest that ustekinumab might be an effective therapy in systemic lupus erythematosus.
Patients with systemic lupus erythematosus have a high risk for postoperative complications and mortality following major surgery compared with patients without SLE.
Patient-reported outcomes are independent predictors of mortality in systemic lupus erythematosus.
Vaccination rates in patients with systemic lupus erythematosus improved significantly after the implementation of a multifaceted intervention at a rheumatology practice.
Over a 5-year period, the drug was well tolerated and associated with significant declines in urinary protein-creatinine ratio and mean prednisolone dose.
Childhood-onset SLE has major effects on quality of life in adulthood.
The use of validated disease activity and damage metrics is important in the assessment of SLE.
Cigarette smoking was associated with an increased SLE risk and alcohol consumption was associated with decreased SLE risk.
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