Systemic Lupus Erythematosus
Ustekinumab Effective in Phase 2 Study for Systemic Lupus Erythematosus
October 11, 2018Results from a phase 2 study suggest that ustekinumab might be an effective therapy in systemic lupus erythematosus.
Improving Medication Adherence With Drug Monitoring in SLE
October 05, 2018Therapeutic drug monitoring may be useful to help clinicians assess nonadherence in patients with SLE.
Rheumatic Disease Risk Increased in Myasthenia Gravis After Thymectomy
October 03, 2018Data revealed an association between myasthenia gravis and autoimmune rheumatic diseases.
Infectious, Noninfectious Postoperative Complications More Frequent in Patients With SLE
October 01, 2018Patients with systemic lupus erythematosus have a high risk for postoperative complications and mortality following major surgery compared with patients without SLE.
Statin Initiation Reduces Overall Mortality in Systemic Autoimmune Rheumatic Diseases
September 24, 2018The initiation of statin therapy is associated with reduced overall mortality in patients with systemic autoimmune rheumatic diseases.
Patient-Reported Outcomes Predict Mortality in Systemic Lupus Erythematosus
September 24, 2018Patient-reported outcomes are independent predictors of mortality in systemic lupus erythematosus.
Improving Rates of Combination Pneumococcal Vaccination in Patients With SLE
September 21, 2018Vaccination rates in patients with systemic lupus erythematosus improved significantly after the implementation of a multifaceted intervention at a rheumatology practice.
Tacrolimus Possibly Beneficial Long Term in Lupus Nephritis
September 19, 2018Over a 5-year period, the drug was well tolerated and associated with significant declines in urinary protein-creatinine ratio and mean prednisolone dose.
Childhood-Onset Systemic Lupus Erythematosus Negatively Affects Quality of Life in Adulthood
September 17, 2018Childhood-onset SLE has major effects on quality of life in adulthood.
Active SLE Disease Activity, Damage Linked to Greater Mortality
September 04, 2018The use of validated disease activity and damage metrics is important in the assessment of SLE.
Effects of Cigarette Smoking, Alcohol Consumption on SLE Risk in Black Women
August 31, 2018Cigarette smoking was associated with an increased SLE risk and alcohol consumption was associated with decreased SLE risk.
Prolonged Antimalarial Exposure Increases Risk for Elevated Cardiac Biomarkers in SLE
August 29, 2018Prolonged antimalarial therapy and persistent creatine phosphokinase elevation resulted in an increased risk for abnormal brain natriuretic peptide and cardiac troponin.
Are Adverse Pregnancy Outcomes Associated With Accelerated Cardiovascular Events in SLE?
August 28, 2018The risk factors for accelerated cardiovascular disease among young women with SLE remain unclear, with multiple studies producing conflicting results.
High Rate of Subclinical Myocardial Injury in Systemic Lupus Erythematosus
August 27, 2018Patients with systemic lupus erythematosus have a high prevalence of subclinical myocardial injury, as evidenced by raised high-sensitive troponin levels.
Characteristics of Early-Onset SLE Distinguished From Mimicking Conditions
August 15, 2018Patients with early SLE had higher rates of unexplained fever than those with SLE-mimicking conditions.
Lupus Nephritis With Impaired Renal Function Linked to Atherosclerosis in SLE
August 14, 2018Lupus nephritis in combination with impaired renal function is strongly associated with the presence of atherosclerosis in patients with systemic lupus erythematosus.
Outcomes of SLE-Associated Thrombotic Microangiopathy With Acquired ADAMTS13 Deficiency
August 08, 2018Researchers investigated the characteristics and outcomes of patients with systemic lupus erythematosus-associated thrombotic microangiopathy based on their ADAMTS13 inhibitor profiles.
High Risk for Zoster in Cyclophosphamide-Treated SLE, Systemic Vasculitis
August 07, 2018The incidence of zoster is high in systemic vasculitis and in patients with SLE exposed to intravenous cyclophosphamide.
Epidemiology, Clinical Characteristics of Systemic Sclerosis vs SSc-SLE Overlap Syndrome
August 02, 2018Patients with SSc-SLE overlap syndrome were younger at diagnosis, had higher rates of pulmonary arterial hypertension, and less frequently had SSc cutaneous manifestations.
Depression Risk High in Cutaneous, Systemic Lupus Erythematosus
August 02, 2018The risk for depression was increased significantly in patients with systemic lupus erythematosus and cutaneous lupus erythematosus.
Silent Cardiac Impairment May Be Present in New-Onset, Drug-Naive Systemic Lupus Erythematosus
August 02, 2018Data indicate that drug-naive new onset systemic lupus erythematosus was likely to involve silent cardiac impairment.
Poor Preconceptional Cardiovascular Health Affects Pregnancy Outcomes in SLE
July 30, 2018Poor preconception cardiovascular health affects pregnancy outcomes in women with SLE.
Burden of Entheseal Sonographic Changes High in Patients With SLE
July 27, 2018The burden of entheseal sonographic changes was significantly higher in patients with SLE vs healthy participants, especially with respect to active inflammation.
Corticosteroid Use Linked to Risk for Osteonecrosis in Systemic Lupus Erythematosus
July 20, 2018Investigators sought to identify the risk factors for osteonecrosis and to identify the minimal investigations needed to monitor the risk for osteonecrosis in patients with systemic lupus erythematosus.
Patient-Reported Disease Activity Correlates With Adverse Pregnancy Outcomes in RA
July 11, 2018A clear difference exists in the utility of patient-reported measures of disease activity in women with SLE and those with RA.
Examining the Prevalence, Characteristics of Monophasic Disease Course in SLE
June 28, 2018Researchers sought to assess the prevalence and characteristics of monophasic disease course in a defined cohort of patients with SLE.
Comparing Factors Associated With Tubulointerstitial Inflammation in Lupus Nephritis
June 25, 2018Routinely available serologic markers have no correlation with tubulointerstitial damage in patients with lupus nephritis.
Poverty, Neighborhood May Affect Outcomes in Systemic Lupus Erythematosus
June 18, 2018Outcomes in systemic lupus erythematosus are largely influenced by level of poverty, type of neighborhood of residence, and chronic stress.
SLE-DAS Superior to SLEDAI-2K in Detecting Changes in SLE Disease Activity
June 15, 2018To assess validity of SLE-DAS, investigators performed a Spearman's correlation between SLE-DAS, PGA, and SLEDAI-2K at the last follow-up visit.
Cardiac Screening May Not Be Beneficial in SLE With Anti-Ro Antibodies
June 14, 2018Cardiac screening in patients with systemic lupus erythematosus and anti-Ro-positive antibodies does not appear to be beneficial in clinical practice.
Rheumatology Advisor Articles
- Ustekinumab Effective in Phase 2 Study for Systemic Lupus Erythematosus
- Manufacturers Increase Drug Prices Twice as Fast During Drug Shortages
- Ultrasound Can Reveal Renal Medulla Urate Deposits in Tophaceous Gout
- Depression Prevalent Among Individuals With Systemic Sclerosis
- TNF-α Inhibitor Therapy May Benefit Extracellular Matrix Remodeling in Women With RA
- Effects of Statin Use on Pain Outcomes in Knee Osteoarthritis
- MicroRNAs Linked to Increased Cortical Bone Porosity in Postmenopausal Women With History of Fracture
- Giant Cell Arteritis: Examining Challenges in Diagnosis and Treatment
- Manufacturers Increase Drug Prices Twice as Fast During Drug Shortages
- Identifying Warning Signs of Depression in a Fellow Clinician