Systemic Lupus Erythematosus
Predicting Treatment Success in Systemic Lupus Erythematosus-Associated PAH
February 08, 2019Treatment success in systemic lupus erythematosus-associated pulmonary arterial hypertension, as defined by the European Society of Cardiology and the European Respiratory Society, is associated with long-term survival and supports a treat-to-target strategy.
Hepatitis A Vaccine Safe in Childhood-Onset SLE
February 07, 2019Inactivated hepatitis A vaccine may be safe and well tolerated in childhood-onset systemic lupus erythematosus.
Case Study: Systemic Lupus Erythematosus With Lupus Nephritis and Thrombotic Microangiopathy
February 07, 2019A 19-year-old woman presents with complaints of progressive shortness of breath, chest pain, and lower extremity edema over the past month.
Omalizumab Safe, Well-Tolerated in Mild to Moderate Systemic Lupus Erythematosus
February 04, 2019Omalizumab was well tolerated in patients with systemic lupus erythematosus, and was associated with improvement in disease activity.
Lupus Nephritis Therapy Response Predicts Survival Odds
February 04, 2019Complete response to induction therapy is associated with significant 82% decreased odds of death at 12 months.
Novel Disease Activity Tool Validated to Detect Changes in SLE
January 29, 2019Researchers validated the SLE Disease Activity Score with improved sensitivity to change compared with SLE Disease Activity Index.
Kidney Transplantation Increases Survival in Lupus Nephritis Cases
January 28, 2019In a nationwide study, renal transplant recipients with lupus nephritis had a 70% lower risk for all-cause mortality than nonrecipients.
Belimumab May Reduce Organ Damage Progression in Systemic Lupus Erythematosus
January 25, 2019Belimumab with standard of care treatment resulted in lower rates of organ damage accrual compared with standard of care alone.
Clinical Trials in Childhood-Onset Systemic Lupus Erythematosus: Next Steps and Future Directions
January 25, 2019Access to medications for childhood-onset systemic lupus erythematosus is currently limited, partly because of a lack of high-quality evidence from clinical trials.
IgG Autoantibody Profile Examined in Established Systemic Lupus Erythematosus
January 22, 2019Researchers examined the role of epitope spreading in established systemic lupus erythematosus.
Social Support Protective Against Depression in African-American Women With SLE
January 16, 2019Organ damage was positively correlated with depression in women with systemic lupus erythematosus, while social support offered protection against depression.
Urine Immunoassay Identifies Novel Lupus Nephritis Biomarkers
January 15, 2019Using electrochemiluminescence, researchers found 5 urinary proteins that have "reasonable specificity" for lupus nephritis.
Antiphospholipid Score Validated as Risk Factor for Idiopathic Osteonecrosis of the Femoral Head in SLE
December 28, 2018Researchers identified a high antiphospholipid score as a novel risk factor for idiopathic osteonecrosis of the femoral head in patients with systemic lupus erythematosus.
SLE Remission Strongly Linked to Improved Quality of Life
December 27, 2018Disease remission is associated with an improved physical domains of health-related quality of life in patients with systemic lupus erythematosus.
Promising Screening Tools Assessed for Cognitive Dysfunction in Systemic Lupus Erythematosus
December 24, 2018Researchers evaluated the Montreal Cognitive Assessment questionnaire and the Informant Questionnaire on Cognitive Decline in the Elderly as screening tools for cognitive dysfunction in SLE.
Baricitinib Gets Fast Track Status for Systemic Lupus Erythematosus
December 14, 2018Data from a phase 2 trial of baricitinib for the treatment of SLE supporting the Fast Track designation were published in The Lancet and presented at the European Congress of Rheumatology earlier this year.
Antimalarial-Induced Cardiomyopathy May Be Underrecognized in Systemic Lupus Erythematosus
December 13, 2018Researchers described 8 patients with antimalarial-induced cardiomyopathy in a defined systemic lupus erythematosus cohort.
Similar Long-Term Outcomes in Early- vs Late-Onset Lupus Nephritis
December 12, 2018Researchers observed comparable long-term outcomes between patients with late- and early-onset lupus nephritis.
Low-Dose Leflunomide Effective for Treatment of Proliferative Lupus Nephritis
November 29, 2018Data support the clinical efficacy of low-dose leflunomide combined with prednisone for the treatment of proliferative lupus nephritis.
Intrauterine Fetal Death Associated With Antiphospholipid Syndrome
November 27, 2018Intrauterine fetal death may be an early sign of antiphospholipid syndrome in pregnant women.
Psychosis in Systemic Lupus Erythematosus Is Rare, Manageable
November 27, 2018Risk factors for psychosis in SLE included male sex and African ancestry.
Cell-Bound Complement Activation Products May Help Pediatric-Onset SLE Diagnosis
November 26, 2018Researchers examined the role of CB-CAPs for diagnosis and monitoring of pediatric-onset SLE.
Immunogenicity of Pneumococcal Vaccines Examined in Children With SLE
November 21, 2018Investigators evaluated the immunogenicity of pneumococcal vaccination in children with systemic lupus erythematosus.
Positive Coombs Test Without Hemolytic Anemia Predicts Disease Activity in SLE
November 21, 2018A positive direct Coombs test in the absence of hemolytic anemia may be a useful biomarker for assessing disease activity in systemic lupus erythematosus.
High and Low HCQ Levels During Pregnancy Linked to Preterm Birth, Disease Activity in SLE
November 13, 2018High and low HCQ levels were associated with preterm birth and disease activity in SLE.
Long-Term Belimumab Treatment Improves Fatigue, Quality of Life in SLE
November 05, 2018Long-term treatment of SLE with belimumab with standard of care resulted in sustained benefits in patient fatigue and health-related quality of life.
Strong Association Found Between Antiphospholipid Antibodies and First-Time MI
November 05, 2018A strong association between antiphospholipid positivity and first-time MI may represent a risk factor for myocardial infarction.
Identifying Musculoskeletal Manifestations in Systemic Lupus Erythematosus
November 02, 2018Investigators sought to define the clinical association of clinical and imaging definitions of synovitis in patients with SLE with musculoskeletal symptoms.
SERPINA3 Identified as Candidate Urinary Biomarker for Lupus Nephritis Activity
November 01, 2018Researchers identified SERPINA3 as a potential urine biomarker to quantify lupus nephritis.
Cardiovascular Magnetic Resonance Tomography May Detect Cardiac Complications in SLE
October 31, 2018Researchers sought to determine whether a cardiovascular magnetic resonance protocol may be useful for early diagnosis of heart disease in patients with systemic lupus erythematosus.
Rheumatology Advisor Articles
- Vaccination Guidelines Released for Patients With Immune-Mediated Disorders
- Baricitinib Therapy in RA Not Associated With Adverse Cardiovascular Events
- Clinical, Radiographic Benefits of Tofacitinib Sustained for 2 Years in Rheumatoid Arthritis
- Cardiovascular Safety in Gout: Interpreting Data From the CARES Trial
- Axial Disease More Common in Psoriatic Arthritis With Acute Skin Manifestations
- Vaccination Guidelines Released for Patients With Immune-Mediated Disorders
- Does Cold Weather Affect Arthritis and Joint Pain?
- BMD Improved Significantly With Denosumab vs Bisphosphonates in Osteoporosis
- JAK Inhibitor Tapering in Rheumatoid Arthritis: Implications for Patients in Sustained Remission
- Yoga May Help With Rheumatoid Arthritis Symptoms, Severity
- Mycoplasma Pneumonia Increases Risk for Rheumatoid Arthritis
- Effectiveness of Biologic DMARDs in Rheumatoid Arthritis Compared
- Subchondral Pathology Independently Associated With Knee Osteoarthritis
- Yoga May Help With Rheumatoid Arthritis Symptoms, Severity
- Effects of Monetary Bonuses on Physician Care in Chronic Disease