Systemic Lupus Erythematosus
Patients with early SLE had higher rates of unexplained fever than those with SLE-mimicking conditions.
Lupus nephritis in combination with impaired renal function is strongly associated with the presence of atherosclerosis in patients with systemic lupus erythematosus.
Researchers investigated the characteristics and outcomes of patients with systemic lupus erythematosus-associated thrombotic microangiopathy based on their ADAMTS13 inhibitor profiles.
The incidence of zoster is high in systemic vasculitis and in patients with SLE exposed to intravenous cyclophosphamide.
Patients with SSc-SLE overlap syndrome were younger at diagnosis, had higher rates of pulmonary arterial hypertension, and less frequently had SSc cutaneous manifestations.
The risk for depression was increased significantly in patients with systemic lupus erythematosus and cutaneous lupus erythematosus.
Data indicate that drug-naive new onset systemic lupus erythematosus was likely to involve silent cardiac impairment.
Poor preconception cardiovascular health affects pregnancy outcomes in women with SLE.
The burden of entheseal sonographic changes was significantly higher in patients with SLE vs healthy participants, especially with respect to active inflammation.
Investigators sought to identify the risk factors for osteonecrosis and to identify the minimal investigations needed to monitor the risk for osteonecrosis in patients with systemic lupus erythematosus.
A clear difference exists in the utility of patient-reported measures of disease activity in women with SLE and those with RA.
Researchers sought to assess the prevalence and characteristics of monophasic disease course in a defined cohort of patients with SLE.
Routinely available serologic markers have no correlation with tubulointerstitial damage in patients with lupus nephritis.
Outcomes in systemic lupus erythematosus are largely influenced by level of poverty, type of neighborhood of residence, and chronic stress.
To assess validity of SLE-DAS, investigators performed a Spearman's correlation between SLE-DAS, PGA, and SLEDAI-2K at the last follow-up visit.
Cardiac screening in patients with systemic lupus erythematosus and anti-Ro-positive antibodies does not appear to be beneficial in clinical practice.
Baricitinib 4 mg was safe and effective in patients with systemic lupus erythematosus.
Recent data from EULAR 2018 highlight the existence of thrombotic factors in systemic lupus erythematosus.
Obesity is not associated with the development of lupus nephritis among patients with systemic lupus erythematosus.
Investigators sought to evaluate changes in demographic, clinical, and histologic presentation in patients with lupus nephritis between 1970 and 2016.
Female patients with systemic lupus erythematosus who had musculoskeletal symptoms or positive antiphospholipid antibodies demonstrated higher titers of anti-double-stranded DNA antibodies.
The pathogenic pathways of SLE-related cognitive dysfunction are yet to be fully elucidated, but vasculopathy, antibody-mediated neurotoxicity, impairments in cytokine signaling, and complement abnormalities have been proposed as contributing factors.
Recent evidence suggests that systemic sclerosis and SLE in pulmonary arterial hypertension should be considered separate diseases.
Quality of life measurements capture unique information about systemic lupus erythematosus that are not included in disease activity or damage evaluations.
The relationship between pain and cognitive dysfunction was explained by sleep disturbance and depressive symptoms.
Bisphosphonates and vitamin D may help prevent atherosclerosis in patients with systemic lupus erythematosus.
Provisional criteria for global flares in patients with childhood-onset systemic lupus erythematosus are now available from the ACR.
Researchers compared the clinical, laboratory, and treatment characteristics of antiphospholipid antibody-positive patients with or without SLE.
Data show that anti-ENA results change infrequently, especially following 1 or more negative tests.
A 72-year-old Japanese woman with a 40-year history of lupus nephritis presented with leg edema that had lasted for several weeks.
Rheumatology Advisor Articles
- Efficacy of ABT-122 Maintained in Psoriatic Arthritis, Rheumatoid Arthritis at 36 Weeks
- Comorbid Fibromyalgia Influences Disease Activity, Quality of Life in Axial Spondyloarthritis
- Knee Load Associated With Increased Walking Pain in Osteoarthritis
- Pain Catastrophizing Decreases in Rheumatoid Arthritis After DMARD Initiation
- CVD Prevention Measures Inadequate in Patients With Inflammatory Joint Diseases
- Genetic Screening May Predict Osteoporosis, Fracture Risk
- Exploring the Clinical Implications of Cannabinoid Use in Rheumatoid Arthritis
- Diagnosing Lyme Disease in Children With Neuropsychiatric Illness
- Predicting Primary Nonresponse to Methotrexate in Rheumatoid Arthritis
- Prednisone, Prednisolone Does Not Adversely Affect Bone Mineral Density in RA
- Sulfasalazine Reduces Pneumocystis Pneumonia Risk in Rheumatoid Arthritis
- DPP-4 Inhibitors and Incidence of Rheumatoid Arthritis in Type 2 Diabetes
- Response to Certolizumab Pegol at 12 Weeks Predicts Long-Term RA Outcomes
- Performance Phenotypes of Lumbar Spinal Stenosis and OA With Accelerometry Data
- Characteristics of Early-Onset SLE Distinguished From Mimicking Conditions