Predictive Value of Autoantibodies in Clinically Suspect Arthralgia and Risk for RA
The presence of the certain autoantibodies accurately predicts a person’s risk for progression from clinically suspect arthralgia to rheumatoid arthritis.
Antibodies
Low Immunogenicity of Tocilizumab in Rheumatoid Arthritis
Pooled results examine the incidence of antidrug antibody development after both intravenous and subcutaneously administered tocilizumab for rheumatoid arthritis.
Periodontal Pathogen Antibodies Precede RA Symptom Onset
Antibody concentrations against antigen epitopes of the oral pathogen P gingivalis appear to increase prior to the onset of RA symptoms, suggesting that P gingivalis may be associated with RA pathogenesis.
Sclerostin Inhibitor Romosozumab Reduces Fracture Risk Postmenopause
At 24 months, rates of vertebral fractures were significantly lower in the romosozumab group.
Is Post-Vaccination IgG Predictive of Mortality in Systemic Vasculitis?
Low IgG and B cell counts were associated with infection and vaccine response among patients with systemic vasculitis in stable remission.
BLA Filed With FDA for Monoclonal Ab Inhibiting Sclerostin
Amgen and UCB announced the submission of a Biologics License Application (BLA) to the Food and Drug Administration (FDA) for romosozumab for the treatment of osteoporosis in postmenopausal women at increased risk of fracture.
Serum IgG Levels Associated With Prognosis in SLE-AIH
Features distinguishing SLE-AIH from primary AIH were examined by researchers in an effort to improve treatment responses and prognosis
Persistent LAC Positivity Associated With Higher Vascular Damage Scores in AAV
Persistent lupus anticoagulant positivity in patients with antineutrophil cytoplasmic antibody-associated vasculitis is associated with higher Vasculitis Damage Index scores.
Can Periodontal Antigen Antibodies Be Predictive of Clinical Responses to bDMARDs in RA?
Serum immunoglobulin levels against the periodontal antigen Porphyromonas gingivalis peptidylarginine deiminase appear to correlate with the clinical responses to bDMARD therapy in RA
Anti-Smith Antibodies Indicative of Poor Prognosis in Biopsy-Proven LN
The predictive value for future need for immunosuppression of anti-smith antibodies found on biopsy-proven lupus nephritis was evaluated in a retrospective analysis
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