Off-Label Bisphosphonate Use Effective for Edema in Bone Marrow Lesions
IV zoledronic acid and vitamin D reduces volume of bone marrow edema in patients with bone marrow lesions.
Bisphosphonates
The Handoff: Your Week in Rheumatology News – 4/14/17
This week, a phase III trial for investigational drug voclosporin for lupus nephritis treatment was approved, prolonged insomnia may lead to less robust bone formation — causing osteoporosis and bone fractures — and researchers found that women who drink a moderate amount of alcohol daily have a reduced risk of developing systemic lupus erythmatosus.
Predicting Vertebral Fracture Risk After Bisphosphonate Drug Holiday
Study examines the predictive value for vertebral fractures of bone mineral density and bone turnover markers after a 5-year drug holiday.
Postmenopausal Osteoporosis Bisphosphonate Drug Holiday Increases Fracture Risk
A retrospective study examined the risk of developing fractures in postmenopausal women with osteoporosis who discontinued bisphosphonate therapy.
Intensive Bisphosphonate Treatment in Paget’s Disease Lacks Clinical Benefit
Study co-investigator says most recent clinical practice guidelines provide treatment recommendation that is “not based on the evidence” but instead represents “unsubstantiated opinion.”
Osteoporosis Recommendations Alter Bisphosphonate Treatment Trends
Bisphosphonate treatment for osteoporosis among women older than 65 goes up after 2008 recommendations.
Increased Atypical Fracture Rate Associated With Bisphosphonate Treatment in Postmenopausal Asian Women
Researchers examine the association between duration of bisphosphonate treatment and risk of atypical femur fracture in postmenopausal women.
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