Patients with juvenile mixed connective tissue disease had impaired left and right ventricular function compared with matched controls after a median of 15 years disease duration.
Acutely inhaled iloprost improves right ventricular function in terms of RV volume, right ventricular ejection fraction, and RV stroke volume in patients with IPAH and PAH associated with connective tissue disease.
The American College of Rheumatology and Association of Physicians of Great Britain and Ireland have highlighted unmet needs and challenges of connective tissue disease-associated interstitial lung disease.
Vascular EDS is the most severe subtype of Ehlers-Danlos syndrome where patients suffer from life-threatening arterial dissections and ruptures, as well as intestinal and uterine ruptures.
Muscle magnetic resonance imaging may complement a physician’s objective assessment in juvenile dermatomyositis, although negative MRI findings should not preclude treatment continuation.
A better understanding of the natural progression of this disease would allow earlier detection in children at high risk for functional decline.
Researchers used registry data to evaluate the risk of autoimmune diseases over 6.5 years after exposure to HPV vaccines in adolescent and young adult women.
A European committee of pediatric rheumatology experts has provided the first consensus-based recommendations for clinical management of juvenile dermatomyositis.
Post hoc study subgroup analysis shows combination ambrisentan plus tadalafil therapy improves treatment response in patients with connective tissue disease-associated pulmonary arterial hypertension.
Panel advises that up to 50% of young patients with juvenile-onset rheumatic diseases fail to successfully transition to adult rheumatology services.
