Fracture Risk Archives - Rheumatology Advisor

Spondyloarthritis

Increased Risk for Bone Fractures in Patients With Psoriatic Diseases

December 15, 2020

For adults with psoriatic diseases, the likelihood of developing bone fractures is increased.

Osteoporosis

FRAX Without BMD Predicts Risk for Fracture in Adult Type 1 Diabetes

By

Rose Reeb

October 28, 2020

Clinical use of FRAX without bone mineral density can be used to identify adults with type 1 diabetes who are at elevated risk for major osteoporotic fracture.

General Rheumatology

Increased Risk for Nonspinal Fracture in Moderate to Severe Chronic Kidney Disease

By

Natasha Persaud

October 16, 2020

Fracture prevention efforts should be considered in patients with CKD of any age, according to investigators.

Osteoporosis

Hypogonadism May Predict Vertebral Fracture in Patients With Chronic Glucocorticoid Exposure

By

Emily Pond

October 7, 2020

Researchers identified the risk factors associated with fragility fracture development in patients receiving glucocorticoids.

Osteoporosis

Asthma Is Associated With Increased Risk for Osteoporosis

By

Amit Akirov, MD

October 7, 2020

Researchers analyzed the association of asthma and its subgroups with osteoporosis in the Korean adult population, and determined the effects of asthma on osteoporosis based on condition of asthma management.

$bone osteoporosis fracture$

Osteoporosis

Challenges and Strategies in the Management of Osteoporotic and Fragility Fractures During the COVID-19 Pandemic

By

Linda Peckel

September 25, 2020

Several studies have assessed the potentially increased rate and the management of osteoporotic and fragility fractures during the COVID-19 pandemic.

$In patients with HIV, the disease process and ART may contribute to bone loss, resulting in osteopenia or osteoporosis and increased fracture risk.3,10 Proinflammatory cytokines and viral load contribute directly to reduced bone mineral density through their effects on osteoclast and osteoblast activity, inhibiting new bone formation and accelerating bone loss.3 Other risk factors for bone loss or fracture in the HIV population include low body mass index, smoking, substance abuse, glucocorticoid therapy, hypogonadism, coinfection with hepatitis B virus or hepatitis C virus, and vitamin D deficiency (affects ~90% of patients).3,11 Bone loss caused by ART emerges within 1 to 2 years after starting therapy.3,11 Tenofovir-based regimens are associated with higher rates of bone loss.3,11 Guidelines suggest avoiding tenofovir disoproxil fumarate or PI-boosting regimens in patients at high risk.3 Bisphosphonates (eg, alendronate or zoledronate) are recommended for those with HIV who have osteoporosis.3$

General Rheumatology

Obstructive Sleep Apnea Tied to Worse Bone Health

September 23, 2020

History of obstructive sleep apnea (OSA) is independently associated with a higher risk for confirmed vertebral fracture.

ASBMR 2020

Increased Osteoporotic Fracture Risk Among Patients With RA Receiving Oral Glucocorticoids and Proton Pump Inhibitors

By

Emily Pond

September 11, 2020

Researchers assessed the association between concomitant use of oral glucocorticoids and proton pump inhibitors and osteoporotic fracture risk in rheumatoid arthritis.

Female patient in hospital bed looking at xray with clincian

ASBMR 2020

Vascular Calcification in COPD Affects Bone Mineral Density, Increases Fractures

By

Britt Gambino

September 11, 2020

Researchers evaluated the association between osteoporosis and vertebral fragility fractures with cardiovascular calcification in patients with chronic obstructive pulmonary disease.

$Bisphosphonate femur fracture$

Osteoporosis

Increased Risk for Atypical Femur Fracture With Longer Bisphosphonate Use in Women With Osteoporosis

By

Emily Pond

September 8, 2020

Researchers evaluated the association between risk for atypical fracture and duration of bisphosphonate use in women with osteoporosis.