Janssen’s Single-Shot COVID-19 Vaccine Gets Emergency Use Authorization
The EUA was based on data from the randomized, double-blind, placebo-controlled ENSEMBLE trial.
General Rheumatology
JAK Inhibitor and Type I Interferon Possible Treatments for COVID-19
Study authors conducted a systematic review and meta-analysis to assess the efficacy of Janus kinase-inhibitors and Type I interferons as potential antiviral candidates for the treatment of COVID-19.
Text Message System Useful for Monitoring Postoperative Opioid Use
A text message system can monitor postoperative opioid use and shows that many prescribed opioid tablets are unused.
IL-1, IL-6 Inhibition in Patients With COVID-19 and Hyperinflammation Assessed
Researchers compared IL-1 and IL-6 inhibition vs standard management in hospitalized patients with COVID-19, respiratory insufficiency, and hyperinflammation.
Moderna Outlines Strategy for SARS-CoV-2 Variants; Ships Variant Booster to NIH for Testing
The NIAID will evaluate the vaccine candidate, mRNA-1273.351, against the SARS-CoV-2 variant, B.1.351.
Immune Checkpoint Inhibitors Need Not Be Withheld in Patients With Autoimmune Disease
For patients with advanced melanoma, response to immune checkpoint inhibitors is similar for those with and without preexisting autoimmune disease.
Rarest of Them All: Ultra-Rare Rheumatic Diseases – Part 1
In this episode, Jonathan Miner, MD, discusses his contributions to the ultra-rare disease space in rheumatology.
FDA Approves 3D Printed Implant for Avascular Necrosis of the Talus
The FDA has approved the Patient Specific Talus Spacer for humanitarian use in the treatment of avascular necrosis of the ankle joint.
ACR Releases COVID-19 Vaccine Clinical Guidance for Patients With Rheumatic and Musculoskeletal Diseases
The American College of Rheumatology developed clinical guidance for the use of COVID-19 vaccines in patients with rheumatic and musculoskeletal diseases.
Increase in Hydroxychloroquine-Related Adverse Reactions in 2020
The number of ADRs associated with hydroxychloroquine and chloroquine more than doubled in 2020 compared with 2018 and 2019.
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