NIH: Hydroxychloroquine Not Effective for COVID-19
The ORCHID trial was halted in June 2020 after it was determined that hydroxychloroquine was unlikely to benefit hospitalized patients.
General Rheumatology
Disease Burden of Serious Infections Increased in Sjögren Syndrome
Study authors assessed the incidence, time-trends, and outcomes of serious infections in Sjögren syndrome.
Addition of Azithromycin to Hydroxychloroquine Does Not Improve Outcomes in Severe COVID-19
Study authors assessed whether azithromycin in addition to a hydroxychloroquine regimen shows positive results in clinical improvement or mortality reduction in patients hospitalized with severe COVID-19.
Global Burden High for Musculoskeletal Disorders
The global burden of musculoskeletal disorders is considerable, but prevalence and DALYs have decreased slightly since 1990.
Assessing the Effect of Antimalarial Drug Shortages in Rheumatic Disease During the COVID-19 Pandemic
The COVID-19 Global Rheumatology Alliance Patient Experience Survey was used to assess the effect of antimalarial drug shortages during the COVID-19 pandemic.
Neurologic Manifestations of COVID-19 May Involve Cytokine Release Syndrome
Neurologic disturbances in patients with coronavirus disease 2019 were accompanied by evidence of cytokine release syndrome.
Sarcoidosis Diagnosis and Detection: Summary of Clinical Practice Guidelines
Clinicians should use caution when interpreting the guidelines for the diagnosis and detection of sarcoidosis and must consider unique individual clinical circumstances when managing these patients.
Findings Conflicted for Benefit of Tocilizumab in COVID-19
Tocilizumab may be beneficial for adults with COVID-19 admitted to the ICU although other findings are conflicting.
Severe COVID-19 May Not Cause Cytokine Storm
Cytokine levels in severely, critically ill COVID-19 patients are much lower than in other inflammatory syndromes.
Harnessing the Microbiome to Understand Rheumatic Diseases
In this episode, we discuss how the the microbiome can play a role in the potential treatment of rheumatic diseases.
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