Comparing Factors Associated With Tubulointerstitial Inflammation in Lupus Nephritis
Routinely available serologic markers have no correlation with tubulointerstitial damage in patients with lupus nephritis.
Lupus Nephritis
Examining Trends of Histologic Presentation, Renal Outcomes in Lupus Nephritis
Investigators sought to evaluate changes in demographic, clinical, and histologic presentation in patients with lupus nephritis between 1970 and 2016.
Examining Remission Status as a Predictor of Long-Term Renal Survival in Lupus Nephritis
Remission status was a significant and useful predictor of renal survival, in patients with lupus nephritis.
Autoimmune Reactivity to Malondialdehyde in SLE Linked to High Disease Activity, Lupus Nephritis
Researchers investigated serum IgG anti-MDA expression and associations with disease activity in patients with systemic lupus erythematosus.
Mortality, ESRD Incidence Measured in Men vs Women With Lupus Nephritis
No significant differences were observed in the incidence of ESRD and mortality among men vs women with lupus nephritis.
The Handoff: Your Week in Rheumatology News – 4/14/17
This week, a phase III trial for investigational drug voclosporin for lupus nephritis treatment was approved, prolonged insomnia may lead to less robust bone formation — causing osteoporosis and bone fractures — and researchers found that women who drink a moderate amount of alcohol daily have a reduced risk of developing systemic lupus erythmatosus.
SLE Patients With Lupus Nephritis Have Higher Cardiovascular Event Risk
Lupus nephritis a risk factor for some, but not all, cardiovascular outcomes in study of patients with SLE.
Targeted IL-6 Inhibition With Sirukumab Ineffective in Lupus Nephritis
Targeted IL-6 inhibition with sirukumab did not demonstrate efficacy or acceptable safety in patients with active lupus nephritis concomitantly receiving immunosupprsant therapy.
SLE Pregnancy Outcomes Impacted by Maternal Race, Ethnicity
Researchers found significant disparities in pregnancy complications rates and hospitalization costs among white, black, and Hispanic women with systemic lupus erythematosus
Improving Sensitivity of LN Urinary Markers by Combining Panels
Panels of urinary biomarkers were shown to be have increased diagnostic power in predicting complete clinical responses when compared with individual biomarkers.
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