SARS-CoV-2 May Be Linked to Immune-Mediated Myopathy
In this case-control autopsy series, study researchers evaluated skeletal muscle and myocardial inflammations in patients with severe COVID-19 who died.
Myopathy
Integrating Clinical and Laboratory, Biopsy Findings May Help Predict Prognosis of Juvenile Dermatomyositis
Researchers assessed clinical features, muscle biopsy scores, and myositis-specific antibody profiles in juvenile dermatomyositis, and their association with disease outcomes and treatment responses in patients.
Creatine Supplementation May Be Safe, Well Tolerated in Patients With Juvenile Dermatomyositis
Researchers aimed to evaluate the feasibility of studying creatine in juvenile dermatomyositis and to determine the effect of creatine on muscle function and metabolism.
Pharmacologic Management of Type 2 Diabetes May Improve Concurrent Polymyalgia Rheumatica Symptoms
The study authors’ goal was to raise the possibility that some patients with polymyalgia rheumatica and type 2 diabetes mellitus can avoid glucocorticoid treatment.
Evidence Supports Content Validity of Patient-Reported Outcome Measures in Inflammatory Myositis
Researchers investigated the content validity of patient-reported outcome measures in patients with idiopathic inflammatory myopathies.
Cancer Screening Strategies in Rheumatic Diseases: Expert Perspectives
Experts highlight the need for cancer screening strategies in patients with rheumatic diseases.
Examining Treatment Options for Statin-Induced Anti-HMGCR Myopathy
A triple steroid/intravenous immunoglobulin/steroid-sparing immunosuppressant induction strategy was effective for the treatment of statin-induced anti-HMGCR myopathy.
Prominent Muscle Involvement in Dermatomyositis With and Without Anti-Mi2 Autoantibodies
Muscle disease is more prominent among patients with dermatomyositis and anti-Mi2 autoantibodies compared with in those who have anti-Mi2-negative dermatomyositis.
First Clinical Practice Guidelines for Sjögren’s Syndrome Developed
A clinical expert panel from the Sjögren’s Syndrome Foundation has published the first-ever clinical practice guidelines for the disease in the United States.
Exercise May Reduce Impairment in Inflammatory Myopathies
Five randomized controlled trials including adult patients with polymyositis and dermatomyositis (DM) and additional open studies have demonstrated reduced impairment and activity limitation as well as improved quality of life. Exercise can improve muscle aerobic capacity as shown by increased mitochondrial enzyme activity. These data suggest that intensive aerobic exercise and resistance training could reduce disease activity and inflammation and improve muscle metabolism.
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