Osteoporosis Archives - Page 3 of 43

Longer Bisphosphonate Drug Holiday May Increase Fracture Risk

August 14, 2020

In patients who have previously suffered a vertebral fracture, a longer bisphosphonate drug holiday is associated with an increased risk for major osteoporotic fractures.

Spondyloarthritis

Psoriatic Arthritis May Be a Risk Factor for Low BMD, But Association Not Genetically Determined

By

Amit Akirov, MD

August 13, 2020

In this observational study, researchers assessed the association between psoriasis, psoriatic arthritis, and osteoporosis.

Osteoporosis

Teriparatide for Severe Osteoporosis Stabilizes Bone Health in Patients With Duchenne Muscular Dystrophy

By

Morgan E. Meissner

August 6, 2020

Researchers evaluated the safety and efficacy of teriparatide for the treatment of severe osteoporosis in patients with Duchenne muscular dystrophy.

$Bone density indicates future fracture risk.$

Osteoporosis

Orthogeriatric Care Increases Osteoporosis Diagnosis and Treatment in Older Patients With Hip Fracture

By

Morgan E. Meissner

August 6, 2020

In this systematic review, the study authors evaluated the current evidence on orthogeriatric care for older patients with hip fracture.

Osteoporosis

Vertebral Fractures Increased With Long-Term Delay of Denosumab

August 3, 2020

Compared with on-time dosing, delay of denosumab by more than 16 weeks is associated with an increased risk for vertebral fractures.

Osteoporosis

Factors Associated With Development of Osteoporosis and Fragility Fractures in Primary Sjögren Syndrome

By

Morgan E. Meissner

July 31, 2020

Researchers determined the prevalence and factors associated with osteoporosis and fragility fractures in patients with primary Sjögren syndrome.

General Rheumatology

Decrease in Incidence of Hip Fractures From 1970 to 2010

July 31, 2020

The incidence of hip fracture decreased from 1970 to 2010 in the US.

Osteoporosis

Osteoporosis, Sarcopenia Prevalent in Patients With Primary Biliary Cholangitis

By

Emily Pond

July 29, 2020

Primary biliary cholangitis is often associated with diagnoses of osteoporosis, sarcopenia, or vertebral fracture among women, with diagnosis of one condition predicting the diagnosis of another.

Osteoporosis is diagnosed in individuals with a bone mineral density (BMD) T-score of −2.5 or less.11 Patients with RA are twice as likely as the general population to develop generalized osteoporosis.2 Although osteoporosis is more common in women with RA, men are also at risk.12,13 In RA, BMD loss is greater at the peripheral bones than the axial skeleton.2 Data show 17% to 32% of patients with RA have BMD loss at the lumbar spine, and 15% to 36% have BMD loss at the hip.1 Periarticular and generalized osteoporosis may share a similar mechanism. Glucocorticoid use accelerates BMD loss, especially in the first 3 to 6 months.18 Disease duration and activity are strong predictors of osteoporosis risk, but evidence of bone loss is also seen in patients with early, asymptomatic RA.1,2 Another risk factor is sarcopenia, which affects more women than men with RA.1 Patient-related risk factors include postmenopausal status/age, low BMI, immobility, and family history of osteoporosis.1,2,5 Anti-TNF-α blockade appears to reduce the rate of generalized bone loss, possibly by restoring equilibrium between bone resorption and formation.2

Inflammatory Myopathy

Elevated Risk for Osteoporosis and Fracture in Patients With Inflammatory Myositis

By

Morgan E. Meissner

July 23, 2020

Researchers assessed and compared the fracture risk and prevalence of osteoporosis in patients with idiopathic inflammatory myopathy and rheumatoid arthritis.

Osteoporosis

Exposures During Gestation and Infancy May Affect Young Adult Bone Health

July 20, 2020

Factors during gestation and infancy may impact bone health in young adulthood.