FDA Approves Tofacitinib for the Treatment of Active Polyarticular Course Juvenile Idiopathic Arthritis
Patients treated with tofacitinib experienced significantly fewer disease flares compared with placebo.
Pediatric Rheumatology
New Composite Disease Activity Score Assesses Systemic Manifestations of Juvenile Idiopathic Arthritis
An international panel of pediatric rheumatologists created a new score to address a lack in the 4-item JADAS in quantifying the burden of extra-articular manifestations of juvenile idiopathic arthritis.
Genetic Risk Scores May Facilitate Clinical Diagnosis of Juvenile Idiopathic Arthritis
Researchers evaluated the use and performance of genomic risk scores for the clinical diagnosis of juvenile idiopathic arthritis.
Low Rates of Severe Disease, Death Reported in Children With COVID-19
Severe disease and death appear to be rare among children and young people hospitalized with laboratory-confirmed COVID-19.
Prevalence of SARS-CoV-2 in Asymptomatic Children Identified
Prevalence of SARS-CoV-2 in asymptomatic children linked to incidence of COVID-19 in general population.
Type 2 Diabetes May Negatively Affect Bone Density in Youth
Type 2 diabetes may negatively impact bone density around the age of peak bone mass.
Combination Therapy May Benefit High-Risk Patients With Kawasaki Disease
Adding corticosteroids to initial IV immunoglobulin may reduce risk for coronary artery abnormalities.
HBV Screening Beneficial in Immunocompromised Pediatric Patients With Rheumatologic Conditions and IBD
Researchers evaluated the prevalence of serologic immunity against hepatitis B virus in immunocompromised patients with pediatric-onset inflammatory bowel disease and rheumatologic diseases.
Sexual Dimorphism of Systemic Juvenile Idiopathic Arthritis Linked to Immature Neutrophil Signature
Researchers characterized the blood gene signatures of male and female patients with systemic juvenile idiopathic arthritis.
Positivity Rates of SARS-CoV-2 Low Among Children in England
Children in England had low positivity rates of SARSCoV2 during the first COVID-19 pandemic peak and also had a low case-fatality rate.
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