Evidence Supports Content Validity of Patient-Reported Outcome Measures in Inflammatory Myositis
Researchers investigated the content validity of patient-reported outcome measures in patients with idiopathic inflammatory myopathies.
Polymyositis
Case Report: Anti-Ku Antibodies Identified in Systemic Sclerosis-Polymyositis Overlap Syndrome in an Adolescent
Authors of a report presented the case of systemic sclerosis-polymyositis overlap syndrome in an adolescent with anti-Ku antibodies.
Predictors Identified for Myositis-Related Interstitial Lung Disease Mortality
Researchers identified independent predictors of short-term dermatomyositis- or polymyositis-related interstitial lung disease mortality.
Tacrolimus Decreases Glucocorticoid Use in Refractory Myositis-Associated Interstitial Lung Disease
Factors associated with favorable treatment responses to conventional therapy and tacrolimus in myositis-associated interstitial lung disease were examined in a retrospective cohort study.
Polymyositis May Increase Risk of Amyotrophic Lateral Sclerosis
The relationship between PM and ALS could indicate a common pathophysiology.
Increased Incidence of LV Diastolic Dysfunction in PM/DM
Patients with PM or DM had an increased prevalence of cardiac abnormalities, most commonly left ventricular diastolic dysfunction, compared with healthy controls.
Exercise May Reduce Impairment in Inflammatory Myopathies
Five randomized controlled trials including adult patients with polymyositis and dermatomyositis (DM) and additional open studies have demonstrated reduced impairment and activity limitation as well as improved quality of life. Exercise can improve muscle aerobic capacity as shown by increased mitochondrial enzyme activity. These data suggest that intensive aerobic exercise and resistance training could reduce disease activity and inflammation and improve muscle metabolism.
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