Researchers described the efficacy of tofacitinib in reducing pain in patients with inflammatory rheumatic and musculoskeletal diseases, including rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis.
The role of mechanoinflammation in the pathogenesis of psoriatic disease and the presence of entheseal lesions as predictors of the onset of clinical joint disease gain support in a new study.
![The contribution of the HLA gene alone to RA heritability has been estimated to be 11% to 37%. [1] Other genes, such as PTPN22, STAT4, CTLA4, TRAF1, PADI4, IRF5, FCRL3, TNFIP3, TNF-α, miRNAs, CD28, CD40, and TYK2 have been associated with susceptibility to, severity of, activity of, and treatment response to RA. [1]](https://1fxghyessyy2gaob23ygwzph-wpengine.netdna-ssl.com/wp-content/uploads/sites/18/2019/01/thinkstockphotos53747224411_1010913-544x306.jpg)
Researchers investigated serum microRNA levels in PsA and assessed the signature in therapeutic responder vs nonresponder patients with PsA.
Researchers explored the incidence rates of hepatobiliary events in the first 6 months of routine treatment with the biosimilar etanercept or an originator drug in inflammatory joint disease.
The use of a 16-channel hand coil MRI to examine flexor tendon pulley changes may improve the detection of psoriatic arthritis and distinguish it from rheumatoid arthritis.
Recently released guidelines from Japan outline the factors that may influence the choice of biologic agents for treatment in patients with psoriasis.
Disease activity in psoriatic arthritis may be positively correlated with body adiposity, saturated fat consumption, and serum cholesterol levels.
High baseline patient vs evaluator global assessment linked to lower TNFi retention in spondyloarthritis.
Apremilast used for the treatment of psoriasis or psoriatic arthritis is not associated with a high risk of incident treated depression, anxiety, or anxiety plus depression.
Researchers compared the incidence rates of adverse events in tofacitinib clinical trials and real-world observational data for other treatments.
