Unraveling the Mysteries of Novel, Rare Rheumatic Diseases – Part 2
Peter Grayson, MD, of the NIH tells us the story behind the discovery of the new inflammatory syndrome, VEXAS, and the importance of research at a molecular level in rheumatology.
Rare Diseases
Rarest of Them All: Ultra-Rare Rheumatic Diseases – Part 1
In this episode, Jonathan Miner, MD, discusses his contributions to the ultra-rare disease space in rheumatology.
First Treatment for Adult-Onset Still Disease Gets FDA Approval
The FDA has approved Ilaris for the treatment of active Still disease, including adult-onset Still disease.
Omalizumab Demonstrates Effectiveness in Normocomplementemic Urticarial Vasculitis
Investigators characterized the effects and markers of response of omalizumab in normocomplementemic urticarial vasculitis.
Alemtuzumab Treatment for Multiple Sclerosis May Induce Life-Threatening ANCA-Associated Vasculitis
A recent case report examined the adverse effects of alemtuzumab in a patient with relapsing remitting multiple sclerosis.
Identification of a Protein Epitope Targeted by the Kawasaki Disease Antibody Response
A protein epitope targeted by the antibody response in children with Kawasaki disease has been identified.
Plasma Exchange Not Associated With Reduced Incidence of End-Stage Kidney Disease or Death in ANCA Vasculitis
Researchers compared the efficacy of plasma exchange vs no plasma exchange, in terms of end-stage kidney disease or death, in patients with severe ANCA-associated vasculitis.
Anti-IL-1 Agents May Be Effective in the Treatment of Familial Mediterranean Fever in Patients With Colchicine Resistance/Intolerance
Investigators assessed the effectiveness of anakinra and canakinumab in patients with familial Mediterranean fever who were resistant/intolerant to colchicine or who had complications with amyloidosis.
Reslizumab Associated With Significant Reduction in Corticosteroid Use in Eosinophilic Granulomatosis With Polyangiitis
Researchers reported on the outcomes of treatment-refractory, corticosteroid-dependent patients with eosinophilic granulomatosis with polyangiitis with severe asthma.
Endothelial Biomarker Levels Elevated and Linked to Extramuscular Activity in Juvenile Dermatomyositis
Researchers analyzed endothelial biomarker levels in the peripheral blood of patients with juvenile dermatomyositis and their association with disease assessments.
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