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Rheumatoid Arthritis

Specific Disease Comorbidity Affects Long Term Functioning in RA

The course of rheumatoid arthritis (RA) is variable, with outcomes dependent upon the degree of joint damage, the physical functional status of the patient, psychological health, and the presence of comorbid illness such as cardiovascular disease, infection, and B-cell lymphomas. Loss of functional capacity in RA occurs as a result of the summation of loss…

Rheumatoid arthritis (RA) should be suspected in the adult patient who presents with inflammatory polyarthritis. The initial evaluation of such patients requires a careful history and physical examination, along with selected laboratory testing to identify features that are characteristic of RA or that suggest an alternative diagnosis. A thorough medical history with close attention to joint involvement and a complete physical examination to assess for possible joint range-of-motion limitation as well as possible presence of synovitis and extraarticular disease manifestations is crucial to including RA in the differential diagnosis and to prompt further laboratory testing.

Dermatologic Manifestations of Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a symmetric and inflammatory peripheral polyarthritis of unknown etiology. Deformity results from the erosion of cartilage and bone from extension of tendons and ligaments secondary to inflammation. When not diagnosed early in the course of disease or not adequately treated, joint destruction leads to restricted joint range of motion and loss…

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