Review of Global Incidence and Prevalence of Systemic Sclerosis
Study authors conducted a systematic review and meta-analysis on the incidence and prevalence of systemic sclerosis.
Scleroderma
B-Cell Depletion Therapy May Be Safe, Effective for Systemic Sclerosis-Associated Pulmonary Arterial Hypertension
Researchers assessed the safety and efficacy of B-cell depletion for systemic sclerosis-associated pulmonary arterial hypertension.
Tocilizumab Approved for the Treatment of Systemic Sclerosis-Associated Interstitial Lung Disease
The FDA has approved Actemra® (tocilizumab; Genentech) subcutaneous injection for slowing the rate of decline in pulmonary function in SSc-ILD.
Low Back Pain Is a Major Driver of Pain in Very Early Systemic Sclerosis
The researchers conducted an extensive pain assessment of patients with systemic sclerosis, examining pain chronification and its association with disease manifestations.
Esophageal Dysphagia Predicts PPI-Partial Response GERD in Systemic Sclerosis
A team of investigators sought to determine the prevalence of proton pump inhibitor-partial response gastroesophageal reflux disease in patients with systemic sclerosis.
Sitaxsentan Designated Orphan Drug for Systemic Sclerosis
The FDA has granted Orphan Drug designation to TMB-003 (Timber Pharmaceuticals) for the treatment of systemic sclerosis.
Obstetric Complications Common Among Women Who Develop Systemic Sclerosis
Researchers evaluated obstetric complications in women with a systemic sclerosis diagnosis vs the general obstetric population.
Revised CRISS Developed to Improve dcSSc Study Outcome Measures
The performance of 5 core set measure in ACR-CRISS in recent trials was explored, and their ability to discern the active medication group from placebo in patients with diffuse cutaneous systemic sclerosis (dcSSc), was assessed.
Progressive ILD Trends in Systemic Sclerosis-Associated ILD
Close monitoring of patients with systemic sclerosis-associated interstitial lung disease and awareness of the variable course of progression is highly important in considering when to initiate treatment.
Data Support Safety, Efficacy of Abatacept in Early Diffuse Cutaneous Systemic Sclerosis
In this open-label extension study, researchers reported on the safety and efficacy of abatacept in early diffuse cutaneous systemic sclerosis.
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