An Overview of Gastrointestinal Dysfunction in Systemic Sclerosis
Eric Dein, MD, discusses the pathophysiology, presentation, diagnostic approach, and symptom management of gastrointestinal dysmotility in systemic sclerosis.
Scleroderma
New Scale Provides Faster Assessment of Patient-Reported Outcomes in Systemic Sclerosis
A 17-item functional scale represents a new patient-reported outcome tool to assess global activities and participation in patients with systemic sclerosis.
Nintedanib Approved for Chronic Fibrosing Interstitial Lung Disease With Progressive Phenotype
The FDA has approved Ofev (nintedanib; Boehringer Ingelheim) for the treatment of patients with chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype.
Intravenous Cyclophosphamide Pulse Therapy May Be an Effective Treatment Option for Skin Fibrosis in SSc
Researchers examined the effect of intravenous cyclophosphamide pulse therapy on skin thickening in patients with systemic sclerosis.
Better Survival in Patients With SSc-Mixed Connective Tissue Disease and SSc-Overlap vs SSc-Only
Researchers described the clinical characteristics and outcomes of systemic sclerosis (SSc)-mixed connective tissue disease and SSc-overlap.
Adverse Outcomes After Percutaneous Coronary Intervention More Prevalent in SSc, SLE
Patients with systemic sclerosis and systemic lupus erythematosus were found to be at increased odds of adverse clinical outcomes and bleeding, respectively, after percutaneous coronary intervention.
Leveraging ECG Markers to Predict Ventricular Arrhythmia in Systemic Sclerosis
Researchers evaluated whether certain electrocardiogram parameters reflecting ventricular repolarization may help in identifying scleroderma in patients with increased risk for ventricular arrhythmias.
Evidence-Based European Consensus Statements for the Management of Interstitial Lung Disease in Systemic Sclerosis
Researchers developed the first expert consensus for the identification and management of interstitial lung disease in systemic sclerosis.
Examining Associations Between Sex, Autoantibodies, and Microangiopathy in Systemic Sclerosis
Researchers evaluated the effect of sex or expression of specific antinuclear autoantibodies on the degree of microangiopathy in systemic sclerosis.
Systemic Sclerosis Myocarditis Associated With Higher Degrees of Myocardial Fibrosis
Systemic sclerosis myocarditis was found to occur more frequently in individuals with heart failure and a higher dyspnoea class, and to be associated with higher degrees of myocardial fibrosis.
