Tapering DMARD Therapy in Rheumatoid Arthritis

Use of conventional synthetic and biologic disease-modifying antirheumatic drugs (DMARDs) have substantially improved patient outcomes during the past 30 years, with many patients showing low disease activity or achieving full disease control.[1]

For those having no signs or symptoms of disease activity, tapering or even discontinuing treatment might be beneficial; however, appropriate DMARD de-escalation requires proper patient selection that carefully weighs the benefits of remission against the risks of relapse, safety concerns, and treatment costs.[1]

Hallmarks of Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is a long-term autoimmune disorder that may affect the skin, joints, kidneys, brain, and other organs. Although factors such as sunlight, certain drugs and viral infections are known to trigger SLE, the underlying cause is not fully understood. Because SLE is uncommon – it currently affects approximately 40 to 50 persons…

A ring-like swelling towards the fingertip, common in individuals with osteoarthritis, which is formed by a lump of cartilage-covered bone around the terminal joint. Osteoarthritis most commonly affects the elderly.

Arthritis Classifications

Arthritis is the inflammation of one or more joints. The condition occurs when cartilage that normally protects the joints breaks down, causing the bones to rub together. This results in pain, swelling, stiffness, and limited motion. As many as 37 million Americans have arthritis with etiologies ranging from autoimmune disorders to infection to general wear…

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