Belimumab Shows Long-Term Safety, Efficacy in Lupus Nephritis
The proportion of patients with lupus nephritis achieving renal response with belimumab increased during a 6-month extension study.
Systemic Lupus Erythematosus
Impaired Hand Function and Daily Activities Significant Even Among Patients With Low Disease Activity in SLE
Researchers assessed hand function and performance in activities of daily living in patients with systemic lupus erythematosus vs healthy individuals.
Anifrolumab Improves Skin and Joint Disease Activity in Patients With Systemic Lupus Erythematosus
According to data from a press release, which were later presented at the EULAR 2021 Virtual Congress, “Anifrolumab was consistently associated with improvements in both skin rash and arthritis across three different disease measures…in patients with moderate to severe SLE.”
Patients With Arthritis, Lupus Demonstrate Increased Resilience to Hydroxychloroquine Retinal Toxicity
The protection persisted, even though patients in the resilient group received a significantly higher total dose.
Voclosporin Plus MMF and Steroids Provide Superior Renal Response vs Placebo in Lupus Nephritis
Researchers aimed to evaluate the efficacy and safety of calcineurin inhibitor voclosporin for the treatment of lupus nephritis.
From Bedside to Benchtop: A Reverse Translational Approach to Study Human Lupus Nephritis Mechanisms Using Mouse Models
For Arthritis Awareness Month, Paul Hoover, MD, and colleagues provide insight into the research conducted by their team on understanding human lupus nephritis mechanisms using mouse models.
Review Highlights Disparities in SLE, LN Care Among Medicaid Beneficiaries
Medicaid patients with SLE or lupus nephritis have worse outcomes compared with privately insured patients, research shows.
Increased SELENA-SLEDAI Score Correlates With Organ Damage, Death in SLE
Researchers evaluated the effect of mild to moderate systemic lupus erythematosus disease activity on the risk for organ system damage and death.
Protein Marker May Predict ESKD Risk in Membranous Lupus Nephritis
In a study, approximately one-third of patients with lupus membranous nephritis tested positive for the proteins exostosin 1/exostosin 2.
ST-T/T-Wave Changes Most Common ECG Abnormalities in SLE; Age, Disease Duration and Activity Are Risk Factors for Abnormalities
Researchers determined the prevalence of ECG abnormalities in patients with SLE and examined the factors associated with ECG abnormalities using machine learning.
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