Higher Risk for Cancer in Younger Women With Systemic Lupus Erythematosus
Researchers estimated the incidence of cancer in patients with systemic lupus erythematosus differentiating between hormone-sensitive and nonhormone sensitive cancers.
Systemic Lupus Erythematosus
Hydroxychloroquine Blood Level Testing May Predict Retinopathy in SLE
Researchers addressed the role of hydroxychloroquine blood levels in identifying risk for retinopathy in patients with systemic lupus erythematosus.
Less Stringent SLE Remission Definitions May Be Insufficiently Distinct From LLDAS
Researchers assessed the attainability and effect of the Definitions of Remission in Systemic Lupus Erythematosus (SLE) compared with the lupus low disease activity state in patients with SLE.
Low-Dose IL-2 May Be Safe, Effective in the Treatment of Systemic Lupus Erythematosus
Researchers evaluated the safety and efficacy of low-dose IL-2 therapy in systemic lupus erythematosus in a double-blind and placebo-controlled trial.
Patients With Systemic Lupus Erythematosus More Likely to Use Opioids
Patients with SLE are more likely to use opioids than persons without SLE, and most SLE patients who use opioids do so for more than one year.
2017 Weighted Criteria Validated for Pediatric Systemic Lupus Erythematosus
Researchers validated the 2017 weighted, 1997 ACR, and 2012 SLICC criteria and compared their sensitivities and specificities in patients with pediatric systemic lupus erythematosus.
Obinutuzumab Gets Breakthrough Status for Treatment of Lupus Nephritis
The FDA has granted Breakthrough Therapy designation to obinutuzumab (Genentech), a CD20-directed cytolytic antibody, for the treatment of adults with lupus nephritis.
Simplified Scoring System Differentiates CNS Infections From Neuropsychiatric SLE
Researchers analyzed the clinical features and outcomes of infections in the central nervous system (CNS) in patients with systemic lupus erythematosus (SLE) and created a simplified scoring system to differentiate CNS infections from neuropsychiatric SLE.
Biopsy-Informed Management Safely, Accurately Predicts Flares in Lupus Nephritis
This study reports the long-term renal outcomes of kidney biopsies performed at prespecified intervals to determine the safety and accuracy of tapering of maintenance immunosuppression.
2019 EULAR/ACR Recommendations for SLE Classification Criteria
New 2019 classification criteria for systemic lupus erythematosus was jointly developed by the European League Against Rheumatism (EULAR) and the American College of Rheumatology (ACR).
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