Visual Analog Scale Assessments Can Reliably Assess Disease Severity in SLE
Researchers compared the performance of 2 visual analog scale-based assessments, SSPGA and LFA-REAL, with outcome measures from other lupus trials.
Systemic Lupus Erythematosus
Renal Arteriosclerosis Develops Prematurely in Lupus Nephritis
A study found that renal arteriosclerosis develops 2 decades earlier in patients with lupus nephritis compared with healthy age-matched controls.
High Genetic Risk Score Associated With Organ Damage, Renal Dysfunction, and All-Cause Mortality in SLE
The study evaluated the association between high genetic disease risk and disease severity in patients with systemic lupus erythematosus.
Peripheral Nervous System Disease Has Significant Negative Effect on Quality of Life in SLE
Peripheral nervous system (PNS) disease is a component of systemic lupus erythematosus (SLE) disease activity and has a significant negative impact on health-related quality of life.
Antimalarial Drugs May Reduce Polyautoimmunity in Systemic Lupus Erythematosus
Researchers evaluated the frequency of polyautoimmunity and its associated factors in a large retrospective cohort of patients with systemic lupus erythematosus.
Belimumab Associated With Meaningful Improvement in Lupus Nephritis Trial
GlaxoSmithKline announced positive results from the phase 3 BLISS-LN trial of belimumab for the treatment of active lupus nephritis in adult patients.
Anifrolumab Improves Response at 52 Weeks in Lupus
For patients with systemic lupus erythematosus (SLE), anifrolumab is associated with improved response at 52 weeks versus placebo.
Itolizumab Receives Fast Track Status for Lupus Nephritis
The FDA has granted Fast Track designation for itolizumab (EQ001; Equillium) for the treatment of lupus nephritis.
No Significant Effect of Belimumab on Levels of Certain Anticardiolipin Antibodies in SLE
Researchers assessed the effect of belimumab vs placebo on antiphospholipid antibodies from 2 large randomized controlled trials, BLISS-76 and BLISS-52.
Voclosporin Superior to Standard of Care in Lupus Nephritis Trial
Voclosporin was found to be superior to standard-of-care treatment in patients with lupus nephritis, according to data from the phase 3 AURORA trial.
Next post in Systemic Lupus Erythematosus
