Lupus Nephritis Therapy Response Predicts Survival Odds
Complete response to induction therapy is associated with significant 82% decreased odds of death at 12 months.
Systemic Lupus Erythematosus
Novel Disease Activity Tool Validated to Detect Changes in SLE
Researchers validated the SLE Disease Activity Score with improved sensitivity to change compared with SLE Disease Activity Index.
Kidney Transplantation Increases Survival in Lupus Nephritis Cases
In a nationwide study, renal transplant recipients with lupus nephritis had a 70% lower risk for all-cause mortality than nonrecipients.
Belimumab May Reduce Organ Damage Progression in Systemic Lupus Erythematosus
Belimumab with standard of care treatment resulted in lower rates of organ damage accrual compared with standard of care alone.
Clinical Trials in Childhood-Onset Systemic Lupus Erythematosus: Next Steps and Future Directions
Access to medications for childhood-onset systemic lupus erythematosus is currently limited, partly because of a lack of high-quality evidence from clinical trials.
IgG Autoantibody Profile Examined in Established Systemic Lupus Erythematosus
Researchers examined the role of epitope spreading in established systemic lupus erythematosus.
Social Support Protective Against Depression in African-American Women With SLE
Organ damage was positively correlated with depression in women with systemic lupus erythematosus, while social support offered protection against depression.
Urine Immunoassay Identifies Novel Lupus Nephritis Biomarkers
Using electrochemiluminescence, researchers found 5 urinary proteins that have “reasonable specificity” for lupus nephritis.
Antiphospholipid Score Validated as Risk Factor for Idiopathic Osteonecrosis of the Femoral Head in SLE
Researchers identified a high antiphospholipid score as a novel risk factor for idiopathic osteonecrosis of the femoral head in patients with systemic lupus erythematosus.
SLE Remission Strongly Linked to Improved Quality of Life
Disease remission is associated with an improved physical domains of health-related quality of life in patients with systemic lupus erythematosus.
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