Phase 3 Trial of Janssen’s COVID-19 Vaccine to Evaluate Single Dose Regimen
A phase 3 trial evaluating the vaccine candidate, JNJ-78436735 (Ad26.COV2.S; Janssen), for the prevention of COVID-19 has been initiated.
Systemic Lupus Erythematosus
Hydroxychloroquine Tied to Heart Problems Prior to Pandemic
Real-world, pre-COVID-19 adverse events data show hydroxychloroquine and chloroquine are associated with cardiovascular adverse events.
New SLE Classification Criteria Perform Well in Early Disease and Across Sexes, Ethnicities
Researchers evaluated the performance of 2019 EULAR/ACR classification criteria for systemic lupus erythematosus, with regard to disease duration, sex, and race/ethnicity.
Newly Diagnosed SLE Could Potentially Be Drug Induced
A new case of cutaneous lupus erythematosus or systemic lupus erythematosus could potentially be drug induced.
Treatment With Hydroxychloroquine Plus Azithromycin Linked to Cardiovascular Mortality in Rheumatoid Arthritis
Researchers assessed the safety of hydroxychloroquine alone and in combination with azithromycin to determine the risk associated with its use in routine care in rheumatoid arthritis.
Pulmonary Arterial Compliance May Predict Mortality in SLE-Associated PAH
Pulmonary arterial compliance was found to be strongly associated with all-cause mortality and clinical worsening in patients with systemic lupus erythematosus-associated pulmonary arterial hypertension.
Self-Reported Frailty Prevalent Among Patients With Rheumatic Musculoskeletal Diseases
Researchers described the prevalence of self-reported frailty among patients with rheumatic musculoskeletal diseases and its associated factors.
Assessing Risk for Ovarian Dysfunction With Intravenous Cyclophosphamide in Women With Severe Lupus
Researchers evaluated the risk for ovarian dysfunction with cyclophosphamide use in women with severe lupus.
Low Platelet Distribution Width May Predict Lupus Nephritis
Patients with systematic lupus erythematosus who have a low platelet distribution width are more likely to have lupus nephritis.
Cosmetic Camouflage for Permanent Facial Lesions in SLE Associated With Improved Quality of Life
Researchers investigated the effect of cosmetic camouflage on health-related quality of life in women with SLE and permanent facial skin damage.
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