Voclosporin Granted Priority Review for Lupus Nephritis
The FDA will give Priority Review to the New Drug Application (NDA) of voclosporin for the treatment of lupus nephritis.
Systemic Lupus Erythematosus
Hydroxychloroquine During Pregnancy May Prevent Congenital Heart Block
For anti-SSA/Ro-positive mothers with a previous pregnancy complicated by congenital heart block (CHB), hydroxychloroquine may reduce the recurrence of CHB.
Antibodies Against DNA Complexes Linked to Bacteriuria and Flares in Systemic Lupus Erythematosus
Investigators assessed whether curli/eDNA complexes induced an immune response in patients with systemic lupus erythematosus.
Blood Pressure Dipping May Be a Marker of Cardiovascular Function in Pediatric-Onset SLE
Researchers evaluated blood pressure dipping as a marker of endothelial function and subclinical atherosclerosis in pediatric-onset systemic lupus erythematosus.
Ethnic and Gender Disparities in Rheumatology Care: A Call to Action
In this episode, we highlight and address the disproportionate burden of rheumatic diseases and COVID-19 in ethnic minorities and the gender disparities observed in rheumatology care.
Trial Investigating Ustekinumab for Systemic Lupus Erythematosus Discontinued
Janssen has decided to discontinue the phase 3 LOTUS study evaluating ustekinumab (Stelara®) for the treatment of systemic lupus erythematosus.
SLE May Have Early Effect on Peripheral Nerve Function Before Electrophysiologic or Clinical Neuropathy Development
Researchers determined whether SLE could have an early effect on peripheral nerve function before the development of electrophysiologic abnormalities.
Lack of EULAR/ERA-EDTA Response Predicts Chronic Kidney Disease in Patients With Lupus Nephritis
Researchers evaluated EULAR/ERA-EDTA response to therapy in patients with lupus nephritis.
Inclusion of Non-Criteria Features to SLE Classification Improves Diagnostic Accuracy
Researchers identified criteria and non-criteria features associated with SLE, which can be used in classification criteria.
Belimumab Plus Standard Lupus Nephritis Therapy Improves Renal Responses
Adding belimumab to standard therapy for lupus nephritis is associated with better renal outcomes compared with standard therapy alone.
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