We at Rheumatology Advisor are thankful for you, our readers. As we ponder the truth behind the tryptophan myth, we hope you enjoy this Thanksgiving weekend edition of The Handoff.


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–A Yale University-led team of researchers have identified a gene that increases an individual’s risk of severe rheumatoid arthritis (RA), which may pave the way to individualized RA treatment based on patient’s genetic profiles.

–Theranos take 2? Genalyte, a laboratory testing company, raised $36 million dollars in venture capital funding for its Maverick Detection System, a platform designed to improve blood testing turnaround time. Two pilot studies (linked here and here) presented at the American College of Rheumatology annual meeting compared results of its diagnostic testing vs standard lab testing at rheumatology clinics and tertiary care centers.

–A study published in Neurology links maternal RA to an increased risk of childhood epilepsy; paternal RA was found to have no effect.

–The 2016 Psoriatic Arthritis (PsA) in America national survey conducted by Health Union indicates that patients with PsA often experience a lengthy, frustrating diagnosis process.

–Research published in Arthritis Research & Therapy suggests that treat-to-target strategies may help guide treatment decisions in systemic lupus erythematosus (SLE). The SLE clinical treatment target, designated as the lupus low disease activity state (LLDAS), was retrospectively validated to reduce disease damage accrual when targeted.

–Hydroxychloroquine and abatacept were recently reported to decrease risk of incident diabetes mellitus development in patients with RA, while statin use was associated with increased risk.

–Electronic “pings” regarding herpes zoster vaccination eligibility significantly improved vaccination rates in patients with RA with minimal clinician effort, according to research published in the Journal of Rheumatology.

–Benjamin Nowell, PhD, LMSW, director of patient-centered research at Global Healthy Living Foundation and CreakyJoints, sat down with Rheumatology Advisor to discuss shared decision making in rheumatology. Watch the video below. 

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